The genetic key to bipolar disorder
In the largest study conducted to date on the genetics of bipolar disorder, researchers have identified 36 genes linked to the condition. This marks a significant step toward understanding the genetic factors behind bipolar disorder, which could lead to improved diagnosis and treatment in the future.
Together with a large international research consortium, Kevin O’Connell and Ole Andreassen have conducted the most extensive study on bipolar disorder and genetics to date, involving over 2.9 million people. The findings are published in the prestigious journal Nature, with O'Connell and Andreassen as first and last author respectively.
Links:
Comprehensive popular science article about the findings, from the UiO home page:
The genetic key to bipolar disorder (by Julie Nybakk Kvaal, UiO)
The Nature article:
O’Connell, K. S., Koromina, M., Van der Veen, T., Boltz, T. David, F. S., et al. 2025. Genomics yields biological and phenotypic insights into bipolar disorder. Nature. https://www.nature.com/articles/s41586-024-08468-9