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Oslo University Hospital has awarded 6 excellent articles for the second half-year of 2023

In order to stimulate excellent research and draw attention to the hospital's research activity, Oslo University Hospital rewards outstanding publications every half-year.

Six research groups were awarded for their excellent papers published the second half-year of 2023 during a ceremony on June 7th. Each group received NOK 50.000 earmarked for further research, and the prize winners gave short presentations of their main findings.

Anita Sveen’s project group publish in Nature Communications

The Computational Oncology project group, led by Anita Sveen, has in collaboration with additional members of the Lothe group and clinical partners at OUH published a study on transcriptomic tumor heterogeneity of colorectal cancers.
Gene expression analysis of approximately 1,100 samples from primary tumors and liver metastases of 700 patients treated at OUH was used to define patterns of heterogeneous and uniform expression across tumor regions.

A versatile Fc technology broadly applicable in antibody design aiming for long-acting prophylactic or therapeutic interventions

First author Stian Foss (left) and senior author Jan Terje Andersen
First author Stian Foss (left) and senior author Jan Terje Andersen

In a paper published in Nature Communcations, the laboratory of Professor Jan Terje Andersen and collaborators report on a novel antibody constant region (Fc) variant that is designed to give antibodies broad biodistribution and make them long-acting in the body. These features allow the antibodies to reach the site of action at high concentrations, and the improvements in pharmacokinetics are expected to increase patient convenience, treatment adherence and reduce costs for the healthcare system. This is particularly important for treatment of life-long chronic diseases and for prophylactic treatment of severe infections. The findings have been covered by several media outlets.

Jan Terje Andersen elected as a member of The Norwegian Academy of Science and Letters

Jan Terje Andersen (photo; Thomas B. Eckhof)
Jan Terje Andersen (photo; Thomas B. Eckhof)

Jan Terje Andersen, head of the Adaptive Immunity and Homeostasis research group, has been elected as a new member of the The Norwegian Academy of Science and Letters.  The Academy was founded in 1857 and is an interdisciplinary meeting place for outstanding researchers. It has both Norwegian and foreign members who are elected through a formal process.

- It is a great honor to be elected to the Norwegian Academy of Sciences. I am both happy and grateful. It is an institution with long traditions and a meeting place for professional work and great discussions, where I look forward to participating, says Professor Jan Terje Andersen.

The Annual report from Institute for Cancer Research is published

The annual report for 2023 from the Institute for Cancer Research at Oslo University Hospital is now available online. The eleven key topics of the report describe the work and output from ICR in 2023. Alongside outstanding research and key figures, the report includes information about how we work with recruitment, training, and career development, translation and innovation, dissemination, and public outreach, and collaboration in Norway and abroad.

Our 377 employees in 6 research departments, 26 research groups, 29 project groups, and 6 core facility units represent a vibrant research environment producing high-quality research from basic research to clinical trials.

Mi Stjernberg with Top Cited Article 2022-2023 in Acta Anaesthesiologica Scandinavica

Mi Stjernberg
Mi Stjernberg

Mi Stjernberg is an intensive care nurse and PhD student at the Division of Emergencies and Critical Care, where she is a member of the Perioperative anaesthesiology research group and associate member of the Nursing research group. She has studied how day surgery breast cancer patients experience the first 24 h after returning home, with focus on post-operative pain, nausea and patient satisfaction. The article is one of the most cited in Acta Anaesthesiologica Scandinavica 2022-2023.

 

Heart research award to Kristina Haugaa

Kristina Haugaa
Kristina Haugaa

Professor Kristina Haugaa was presented with the Heart Research Award by HRH Crown Princess Mette-Marit during a ceremony on 15 April. The prize is awarded by the National Association for Public Health and is given to a researcher in Norway who meets high professional goals and who can demonstrate significant results in the heart field. Haugaa, who is professor at the Department of Clinical Medicine, University of Oslo and consultant at Oslo University Hospital, received the award for her pioneering work focusing on preventing sudden cardiac death due to genetic heart defects.

- This award means a lot. First and foremost, it is important for all patients with hereditary heart diseases and their families, says Haugaa, and continues:

- The prize is of course also important for me and my research team. We have worked together for many years with research into hereditary heart diseases. It's really nice to be recognized for this.

Participants wanted forPhoto project to portray people with cancer

Sigrid S. Skånland
Sigrid S. Skånland

Cancer patients are often shown as stereotypes in the media – a person without hair in a hospital bed. Sigrid S. Skånland wants to change this by showing the diversity of people with cancer through portraits. 

Sigrid S. Skånland is a researcher and project leader at the Institute for Cancer Research. She was awarded the “Researcher of the Year” prize in 2023 for the work she does on developing and implementing precision medicine for patients with blood cancer. She has spent the last decade studying patient cells in the lab and says she would like to interact more with the patients.

Audun Kvalvaag contributes to articles in Science Immunology and Nature Immunology

Audun Kvalvaag
Audun Kvalvaag

Researcher Audun Kvalvaag at Department of Molecular Cell Biology (MCB) and Centre for Cancer Cell Reprogramming (CanCell) is a specialist on activation of cytotoxic T cells, and he has recently been involved in collaborations with Elliot Philips in Xiang-Peng Kong´s group at New York University Grossman School of Medicine, and with Pablo Céspedes and Megat Hamid at Chinese Academy of Medical Sciences Oxford Institute, University of Oxford. This has resulted in articles in two highly prestigious immunology journals, Science Immunology and Nature Immunology. Both papers elucidate mechanisms involved in T cell mediated tumour control and may represent novel avenues for immunotherapeutic cancer treatment.


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