Light Meets Precision:
EIC Pathfinder Project SCALPEL Pioneering a Revolutionary Photoimmunotherapy for Cancer
Theo Theodossiou, Project coordinator
In a groundbreaking effort to revolutionise modern oncology, the SCALPEL project launches a Europe wide initiative aimed at redefining cancer treatment by using light to precisely ‘click’ tags to cancer cells, enabling the immune system to recognise and destroy them with unparalleled accuracy. Project coordinator is Theo Theodossiou, head of the Protonics project group at the Department of Radiation Biology at OUH.
The multidisciplinary initiative funded by the European Innovation Council Pathfinder programme under Horizon Europe with a total budget of more than EUR 4 million aims to revolutionise modern oncology offering new hope for millions worldwide.
Published in Level 2 journals, first or last author from Oslo University Hospital.
Mäki-Marttunen V, Nieuwenhuis ST(2025) Neuromodulatory influences on propagation of traveling waves along the unimodal-transmodal gradient Cereb Cortex, 35(7) DOI 10.1093/cercor/bhaf183, PubMed 40663649
Skourti E, Seip K, Mensali N, Jabeen S, Juell S, Øynebråten I, Pettersen S, Engebraaten O, Corthay A, Inderberg EM, Dolznig H, Mælandsmo GM, Egeland EV, Prasmickaite L(2025) Chemoresistant tumor cell secretome potentiates immune suppression in triple negative breast cancer Breast Cancer Res, 27(1), 131 DOI 10.1186/s13058-025-02082-x, PubMed 40660361