Light Meets Precision:
EIC Pathfinder Project SCALPEL Pioneering a Revolutionary Photoimmunotherapy for Cancer
Theo Theodossiou, Project coordinator
In a groundbreaking effort to revolutionise modern oncology, the SCALPEL project launches a Europe wide initiative aimed at redefining cancer treatment by using light to precisely ‘click’ tags to cancer cells, enabling the immune system to recognise and destroy them with unparalleled accuracy. Project coordinator is Theo Theodossiou, head of the Protonics project group at the Department of Radiation Biology at OUH.
The multidisciplinary initiative funded by the European Innovation Council Pathfinder programme under Horizon Europe with a total budget of more than EUR 4 million aims to revolutionise modern oncology offering new hope for millions worldwide.
Published in Level 2 journals, first or last author from Oslo University Hospital.
Schroer L, Weirich S, Hammerstad M, Hersleth HP, Grønsberg IA, Hagen L, Slupphaug G, Malecki JM, Jeltsch A, Falnes PØ, Davydova E(2025) Orthologues of the human protein histidine methyltransferase METTL9 display distinct substrate specificities J Biol Chem, 110318(in press) DOI 10.1016/j.jbc.2025.110318, PubMed 40451431
Wensaas A, Blatti C, Terjesen T, Huhnstock S(2025) Long-term outcome of nonoperative treatment of Perthes' disease : only 19% total hip arthroplasty at a mean follow-up of 48 years Bone Joint J, 107-B(6), 657-662 DOI 10.1302/0301-620X.107B6.BJJ-2024-1310.R1, PubMed 40449542
Yao Z, Fang K, Liu G, Bjørås M, Jin VX, Wang J(2025) Integrated analysis of differential intra-chromosomal community interactions: A study of breast cancer Artif Intell Med, 167, 103180(in press) DOI 10.1016/j.artmed.2025.103180, PubMed 40449144