Visting address: Kirkeveien 166 Bygg 49 0450 Oslo
Postal adress: Oslo Universitetssykehus Postboks 4956 Nydalen 0424 Oslo
Publications 2025
Neurobiological perturbations in bipolar disorder compared to schizophrenia - evidence from cell cultures and brain organoids
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2025.02.012, PubMed 39983953
The Genetic Architecture of Differentiating Behavioral and Emotional Problems in Early Life
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2024.12.021, PubMed 39793691
Correction: Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research
Mol Psychiatry (in press)
DOI 10.1038/s41380-025-02914-4, PubMed 39875590
Maternal seafood intake, dietary contaminant exposure, and risk of juvenile idiopathic arthritis: exploring gene-environment interactions
Front Immunol, 15, 1523990
DOI 10.3389/fimmu.2024.1523990, PubMed 39877361
Subjective cognition in schizophrenia and bipolar disorder: Investigation of group differences and associations with objective cognition and clinical characteristics using a novel measure of subjective cognition
Schizophr Res Cogn, 40, 100345
DOI 10.1016/j.scog.2025.100345, PubMed 39989506
No evidence of positive causal effects of maternal and paternal age at first birth on children's test scores at age 10 years
Nat Hum Behav (in press)
DOI 10.1038/s41562-025-02108-6, PubMed 40016483
Effects of oxytocin administration on non-social executive functions in humans: a preregistered systematic review and meta-analysis
Mol Psychiatry (in press)
DOI 10.1038/s41380-024-02871-4, PubMed 39827218
Polygenic overlap with granulocyte counts identifies novel loci for clozapine metabolism and clozapine-induced agranulocytosis
Neuropsychopharmacology (in press)
DOI 10.1038/s41386-025-02054-x, PubMed 39827279
Exome sequencing identifies novel genes associated with cerebellar volume and microstructure
Commun Biol, 8 (1), 344
DOI 10.1038/s42003-025-07797-3, PubMed 40025133
Gender Differences in Intimate Partner Violence Victimization and Its Relationships With Anxiety, Depression Symptoms and Suicide Behaviours in China
Int J Public Health, 70, 1607953
DOI 10.3389/ijph.2025.1607953, PubMed 40041880
Implementation of the healthy heart tool- an algorithm with potential cardiometabolic health benefits in persons with severe mental illness
BMC Psychiatry, 25 (1), 172
DOI 10.1186/s12888-025-06578-w, PubMed 40001014
Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrum
EBioMedicine, 112, 105576
DOI 10.1016/j.ebiom.2025.105576, PubMed 39889373
Genomics yields biological and phenotypic insights into bipolar disorder
Nature (in press)
DOI 10.1038/s41586-024-08468-9, PubMed 39843750
Estimating Multimodal Structural Brain Variability in Schizophrenia Spectrum Disorders: A Worldwide ENIGMA Study
Am J Psychiatry, appiajp20230806 (in press)
DOI 10.1176/appi.ajp.20230806, PubMed 40007253
Limited evidence of association between dysregulated immune marker levels and telomere length in severe mental disorders
Acta Neuropsychiatr, 37, e4
DOI 10.1017/neu.2024.62, PubMed 39844366
Auditory MMN is associated with the volume of thalamic higher order nuclei in individuals with psychotic disorders and healthy controls
Schizophr Res, 276, 222-233
DOI 10.1016/j.schres.2025.01.031, PubMed 39922063
Long-term physical health conditions and youth anxiety and depression: Is there a causal link?
Psychol Med, 55, e7
DOI 10.1017/S0033291724003271, PubMed 39901647
Mapping the genetic landscape of psychiatric disorders with the MiXeR toolset
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2025.02.886, PubMed 39983952
Social cognitive training among individuals with schizophrenia: Identifying responders to treatment
Schizophr Res Cogn, 40, 100350
DOI 10.1016/j.scog.2025.100350, PubMed 40028173
Publications 2024
COSGAP: COntainerized Statistical Genetics Analysis Pipelines
Bioinform Adv, 4 (1), vbae067
DOI 10.1093/bioadv/vbae067, PubMed 38808072
Finemap-MiXeR: A variational Bayesian approach for genetic finemapping
PLoS Genet, 20 (8), e1011372
DOI 10.1371/journal.pgen.1011372, PubMed 39146375
Poor muscle health and cardiometabolic risks associated with antidepressant treatment
Obesity (Silver Spring), 32 (10), 1857-1869
DOI 10.1002/oby.24085, PubMed 39315407
Caudate nucleus volume in medicated and unmedicated patients with early- and adult-onset schizophrenia
Sci Rep, 14 (1), 22755
DOI 10.1038/s41598-024-73322-x, PubMed 39353988
Increased Herpes simplex virus 1, Toxoplasma gondii and Cytomegalovirus antibody concentrations in severe mental illness
Transl Psychiatry, 14 (1), 498
DOI 10.1038/s41398-024-03198-y, PubMed 39695093
Toxoplasma gondii infection associated with inflammasome activation and neuronal injury
Sci Rep, 14 (1), 5327
DOI 10.1038/s41598-024-55887-9, PubMed 38438515
Genetic associations with psychosis and affective disturbance in Alzheimer's disease
Alzheimers Dement (N Y), 10 (2), e12472
DOI 10.1002/trc2.12472, PubMed 38784964
Assessing causal links between age at menarche and adolescent mental health: a Mendelian randomisation study
BMC Med, 22 (1), 155
DOI 10.1186/s12916-024-03361-8, PubMed 38609914
The effects of oxytocin administration on social and routinized behaviors in autism: A preregistered systematic review and meta-analysis
Psychoneuroendocrinology, 167, 107067
DOI 10.1016/j.psyneuen.2024.107067, PubMed 38815399
The genetic landscape of basal ganglia and implications for common brain disorders
Nat Commun, 15 (1), 8476
DOI 10.1038/s41467-024-52583-0, PubMed 39353893
Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders
J Child Psychol Psychiatry, 66 (3), 350-365
DOI 10.1111/jcpp.14063, PubMed 39462222
The Startle Response and Prepulse Inhibition in Psychosis and Violence: A Combined Electromyography and Electroencephalography Study
Schizophr Bull Open, 6 (1), sgae031
DOI 10.1093/schizbullopen/sgae031, PubMed 39882404
Mental illness and COVID-19 vaccination: a multinational investigation of observational & register-based data
Nat Commun, 15 (1), 8124
DOI 10.1038/s41467-024-52342-1, PubMed 39327436
Altered Sex Differences in Hippocampal Subfield Volumes in Schizophrenia
Schizophr Bull, 50 (1), 107-119
DOI 10.1093/schbul/sbad091, PubMed 37354490
A stratified treatment algorithm in psychiatry: a program on stratified pharmacogenomics in severe mental illness (Psych-STRATA): concept, objectives and methodologies of a multidisciplinary project funded by Horizon Europe
Eur Arch Psychiatry Clin Neurosci (in press)
DOI 10.1007/s00406-024-01944-3, PubMed 39729102
Dissecting unique and common variance across body and brain health indicators using age prediction
Hum Brain Mapp, 45 (6), e26685
DOI 10.1002/hbm.26685, PubMed 38647042
Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
Eur Arch Psychiatry Clin Neurosci (in press)
DOI 10.1007/s00406-023-01725-4, PubMed 38353675
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease
Nat Cardiovasc Res, 3 (6), 754-769
DOI 10.1038/s44161-024-00488-y, PubMed 38898929
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease
Nat Cardiovasc Res, 3 (6), 754-769
DOI 10.1038/s44161-024-00488-y, PubMed 39215135
A 10-Year Longitudinal Study of Brain Cortical Thickness in People with First-Episode Psychosis Using Normative Models
Schizophr Bull, 51 (1), 95-107
DOI 10.1093/schbul/sbae107, PubMed 38970378
Association of Psychological Problems for Which Help Was Sought With Physical Illness
Am J Prev Med (in press)
DOI 10.1016/j.amepre.2024.12.004, PubMed 39667710
Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research
Mol Psychiatry (in press)
DOI 10.1038/s41380-024-02878-x, PubMed 39730880
Depression, anxiety and brain volume after hearing loss and tinnitus: cohort study in the UK Biobank
BJPsych Open, 10 (2), e37
DOI 10.1192/bjo.2023.634, PubMed 38297917
Peripheral vertigo and subsequent risk of depression and anxiety disorders: a prospective cohort study using the UK Biobank
BMC Med, 22 (1), 63
DOI 10.1186/s12916-023-03179-w, PubMed 38336700
Linking menopause-related factors, history of depression, APOE ε4, and proxies of biological aging in the UK biobank cohort
Horm Behav, 164, 105596
DOI 10.1016/j.yhbeh.2024.105596, PubMed 38944998
Mendelian randomization analysis of maternal coffee consumption during pregnancy on offspring neurodevelopmental difficulties in the Norwegian Mother, Father and Child Cohort Study (MoBa)
Psychol Med, 54 (12), 1-14 (in press)
DOI 10.1017/S0033291724002216, PubMed 39382486
Changes in pain during a depressive episode and relationship to cytokine levels in major depressive disorder
Nord J Psychiatry, 78 (3), 181-188
DOI 10.1080/08039488.2023.2290654, PubMed 38251060
Medical comorbidities in bipolar disorder (BIPCOM): clinical validation of risk factors and biomarkers to improve prevention and treatment. Study protocol
Int J Bipolar Disord, 12 (1), 15
DOI 10.1186/s40345-024-00337-8, PubMed 38703295
White matter microstructure in obesity and bipolar disorders: an ENIGMA bipolar disorder working group study in 2186 individuals
Mol Psychiatry (in press)
DOI 10.1038/s41380-024-02784-2, PubMed 39501059
Multimodal workflows optimally predict response to repetitive transcranial magnetic stimulation in patients with schizophrenia: a multisite machine learning analysis
Transl Psychiatry, 14 (1), 196
DOI 10.1038/s41398-024-02903-1, PubMed 38664377
Genetic overlap between Alzheimer's disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence
Mol Psychiatry, 29 (8), 2447-2458
DOI 10.1038/s41380-024-02510-y, PubMed 38499654
Normative Modeling of Brain Morphometry in Clinical High Risk for Psychosis
JAMA Psychiatry, 81 (1), 77-88
DOI 10.1001/jamapsychiatry.2023.3850, PubMed 37819650
Examining intergenerational risk factors for conduct problems using polygenic scores in the Norwegian Mother, Father and Child Cohort Study
Mol Psychiatry, 29 (4), 951-961
DOI 10.1038/s41380-023-02383-7, PubMed 38225381
Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets
Nat Genet, 56 (6), 1310-1318
DOI 10.1038/s41588-024-01771-1, PubMed 38831010
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Nat Genet, 56 (11), 2333-2344
DOI 10.1038/s41588-024-01951-z, PubMed 39433889
Linking sarcopenia, brain structure and cognitive performance: a large-scale UK Biobank study
Brain Commun, 6 (2), fcae083
DOI 10.1093/braincomms/fcae083, PubMed 38510210
Large-scale brainstem neuroimaging and genetic analyses provide new insights into the neuronal mechanisms of hypertension
HGG Adv, 6 (1), 100392
DOI 10.1016/j.xhgg.2024.100392, PubMed 39663699
Genetic and phenotypic heterogeneity in early neurodevelopmental traits in the Norwegian Mother, Father and Child Cohort Study
Mol Autism, 15 (1), 25
DOI 10.1186/s13229-024-00599-0, PubMed 38849897
Author Correction: Characterization of the genetic architecture of infant and early childhood body mass index
Nat Metab, 6 (2), 378
DOI 10.1038/s42255-024-01004-z, PubMed 38337098
Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study
Hum Reprod, 39 (2), 436-441
DOI 10.1093/humrep/dead234, PubMed 37949105
Parental genetically predicted liability for coronary heart disease and risk of adverse pregnancy outcomes: a cohort study
BMC Med, 22 (1), 35
DOI 10.1186/s12916-023-03223-9, PubMed 38273336
Placental efflux transporters and antiseizure or antidepressant medication use impact birth weight in MoBa cohort
iScience, 27 (3), 109285
DOI 10.1016/j.isci.2024.109285, PubMed 38455980
Incidence and Genetic Risk of Juvenile Idiopathic Arthritis in Norway by Latitude
Arthritis Rheumatol (in press)
DOI 10.1002/art.43040, PubMed 39431377
Corrigendum to "Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders" [Psychoneuroendocrinology 157 (2023) 106368]
Psychoneuroendocrinology, 162, 106980
DOI 10.1016/j.psyneuen.2024.106980, PubMed 38336601
Parental education and children's depression, anxiety, and ADHD traits, a within-family study in MoBa
NPJ Sci Learn, 9 (1), 46
DOI 10.1038/s41539-024-00260-8, PubMed 39025869
Gene-based burden tests of rare germline variants identify six cancer susceptibility genes
Nat Genet, 56 (11), 2422-2433
DOI 10.1038/s41588-024-01966-6, PubMed 39472694
Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development
Neurobiol Dis, 203, 106750
DOI 10.1016/j.nbd.2024.106750, PubMed 39608471
Neurostructural subgroup in 4291 individuals with schizophrenia identified using the subtype and stage inference algorithm
Nat Commun, 15 (1), 5996
DOI 10.1038/s41467-024-50267-3, PubMed 39013848
Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles
Schizophrenia (Heidelb), 10 (1), 6
DOI 10.1038/s41537-023-00430-4, PubMed 38182592
Cortical thickness and sub-cortical volumes in post-H1N1 narcolepsy type 1: A brain-wide MRI case-control study
Sleep Med, 116, 81-89
DOI 10.1016/j.sleep.2024.02.031, PubMed 38432031
Assessing regional intracortical myelination in schizophrenia spectrum and bipolar disorders using the optimized T1w/T2w-ratio
Psychol Med, 54 (10), 2369-2379
DOI 10.1017/S0033291724000503, PubMed 38563302
Dissecting the Shared Genetic Architecture of Common Epilepsies With Cortical Brain Morphology
Neurol Genet, 10 (3), e200143
DOI 10.1212/NXG.0000000000200143, PubMed 38817246
Unraveling the shared genetics of common epilepsies and general cognitive ability
Seizure, 122, 105-112
DOI 10.1016/j.seizure.2024.09.016, PubMed 39388989
Associations between parental psychopathology and youth functional emotion regulation brain networks
Dev Cogn Neurosci, 70, 101476
DOI 10.1016/j.dcn.2024.101476, PubMed 39541797
The role of functional emotion circuits in distinct dimensions of psychopathology in youth
Transl Psychiatry, 14 (1), 317
DOI 10.1038/s41398-024-03036-1, PubMed 39095355
Genome-wide association analyses using machine learning-based phenotyping reveal genetic architecture of occupational creativity and overlap with psychiatric disorders
Psychiatry Res, 333, 115753
DOI 10.1016/j.psychres.2024.115753, PubMed 38335777
Polygenic liability for antipsychotic dosage and polypharmacy - a real-world registry and biobank study
Neuropsychopharmacology, 49 (7), 1113-1119
DOI 10.1038/s41386-023-01792-0, PubMed 38184734
How Real-World Data Can Facilitate the Development of Precision Medicine Treatment in Psychiatry
Biol Psychiatry, 96 (7), 543-551
DOI 10.1016/j.biopsych.2024.01.001, PubMed 38185234
Using rare genetic mutations to revisit structural brain asymmetry
Nat Commun, 15 (1), 2639
DOI 10.1038/s41467-024-46784-w, PubMed 38531844
Author Correction: Using rare genetic mutations to revisit structural brain asymmetry
Nat Commun, 15 (1), 3098
DOI 10.1038/s41467-024-47545-5, PubMed 38600109
Distinct Longitudinal Brain White Matter Microstructure Changes and Associated Polygenic Risk of Common Psychiatric Disorders and Alzheimer's Disease in the UK Biobank
Biol Psychiatry Glob Open Sci, 4 (4), 100323
DOI 10.1016/j.bpsgos.2024.100323, PubMed 39132576
Brain asymmetries from mid- to late life and hemispheric brain age
Nat Commun, 15 (1), 956
DOI 10.1038/s41467-024-45282-3, PubMed 38302499
X-chromosome-wide association study for Alzheimer's disease
Mol Psychiatry (in press)
DOI 10.1038/s41380-024-02838-5, PubMed 39633006
Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment
Hum Genomics, 18 (1), 108
DOI 10.1186/s40246-024-00673-x, PubMed 39334510
Rapid Metabolism Underlying Subtherapeutic Serum Levels of Atypical Antipsychotics Preceding Clozapine Treatment: A Retrospective Analysis of Real-World Data
CNS Drugs, 38 (6), 473-480
DOI 10.1007/s40263-024-01079-y, PubMed 38635089
Constructing personalized characterizations of structural brain aberrations in patients with dementia using explainable artificial intelligence
NPJ Digit Med, 7 (1), 110
DOI 10.1038/s41746-024-01123-7, PubMed 38698139
Perinatal depression and risk of maternal cardiovascular disease: a Swedish nationwide study
Eur Heart J, 45 (31), 2865-2875
DOI 10.1093/eurheartj/ehae170, PubMed 38889798
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia
Am J Hum Genet, 111 (7), 1316-1329
DOI 10.1016/j.ajhg.2024.05.017, PubMed 38889728
Principal component analysis as an efficient method for capturing multivariate brain signatures of complex disorders-ENIGMA study in people with bipolar disorders and obesity
Hum Brain Mapp, 45 (8), e26682
DOI 10.1002/hbm.26682, PubMed 38825977
Quantifying the relative importance of genetics and environment on the comorbidity between mental and cardiometabolic disorders using 17 million Scandinavians
Nat Commun, 15 (1), 5064
DOI 10.1038/s41467-024-49507-3, PubMed 38871766
Corrigendum to "Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study" [Schizophr. Res. volume 225 (May 2023) 173-181]
Schizophr Res, 270, 495-496
DOI 10.1016/j.schres.2024.06.029, PubMed 39079354
Telomere biology and its maintenance in schizophrenia spectrum disorders: Exploring links to cognition
Schizophr Res, 272, 89-95
DOI 10.1016/j.schres.2024.08.011, PubMed 39208769
Neurocognitive function and delusion severity in schizophrenia spectrum disorders
Schizophr Res, 270, 172-177
DOI 10.1016/j.schres.2024.06.028, PubMed 38917554
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans
Commun Biol, 7 (1), 432
DOI 10.1038/s42003-024-06101-z, PubMed 38594418
Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling
Proc Natl Acad Sci U S A, 121 (34), e2312511121
DOI 10.1073/pnas.2312511121, PubMed 39141354
Current Auditory Hallucinations Are Not Associated With Specific White Matter Diffusion Alterations in Schizophrenia
Schizophr Bull Open, 5 (1), sgae008
DOI 10.1093/schizbullopen/sgae008, PubMed 39144116
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder
Nat Genet, 56 (5), 792-808
DOI 10.1038/s41588-024-01707-9, PubMed 38637617
More than nature and nurture, indirect genetic effects on children's academic achievement are consequences of dynastic social processes
Nat Hum Behav, 8 (4), 771-778
DOI 10.1038/s41562-023-01796-2, PubMed 38225408
Parental education and income are linked to offspring cortical brain structure and psychopathology at 9-11 years
JCPP Adv, 4 (1), e12220
DOI 10.1002/jcv2.12220, PubMed 38486948
Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease
Brain, 147 (3), 858-870
DOI 10.1093/brain/awad297, PubMed 37671566
Homozygosity for a stop-gain variant in CCDC201 causes primary ovarian insufficiency
Nat Genet, 56 (9), 1804-1810
DOI 10.1038/s41588-024-01885-6, PubMed 39192094
FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Hum Brain Mapp, 45 (2), e26579
DOI 10.1002/hbm.26579, PubMed 38339910
Mismatch negativity and polygenic risk scores for schizophrenia and bipolar disorder
Schizophr Res, 264, 314-326
DOI 10.1016/j.schres.2024.01.013, PubMed 38215567
Eating Problems Among Adolescent Boys and Girls Before and During the Covid-19 Pandemic
Int J Eat Disord, 58 (1), 193-205
DOI 10.1002/eat.24314, PubMed 39473346
Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
Int J Mol Sci, 25 (10)
DOI 10.3390/ijms25105554, PubMed 38791593
Association between a large change between the minimum and maximum monthly values of solar insolation and a history of suicide attempts in bipolar I disorder
Int J Bipolar Disord, 12 (1), 43
DOI 10.1186/s40345-024-00364-5, PubMed 39714599
Hypothalamic Subunit Volumes in Schizophrenia and Bipolar Spectrum Disorders
Schizophr Bull, 50 (3), 533-544
DOI 10.1093/schbul/sbad176, PubMed 38206841
An evolutionary timeline of the oxytocin signaling pathway
Commun Biol, 7 (1), 471
DOI 10.1038/s42003-024-06094-9, PubMed 38632466
Prescriptions of psychotropic and somatic medications among patients with severe mental disorders and healthy controls in a naturalistic study
Nord J Psychiatry, 78 (3), 212-219
DOI 10.1080/08039488.2024.2305806, PubMed 38306243
GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
Commun Biol, 7 (1), 504
DOI 10.1038/s42003-024-06207-4, PubMed 38671141
Partitioning variance in cortical morphometry into genetic, environmental, and subject-specific components
Cereb Cortex, 34 (6)
DOI 10.1093/cercor/bhae234, PubMed 38850213
Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism
Nat Commun, 15 (1), 7550
DOI 10.1038/s41467-024-51947-w, PubMed 39214992
Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease
N Engl J Med, 390 (23), 2217-2219
DOI 10.1056/NEJMc2314334, PubMed 38899702
Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases
BMC Med, 22 (1), 152
DOI 10.1186/s12916-024-03376-1, PubMed 38589871
NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia
Brain Behav Immun, 124, 144-156
DOI 10.1016/j.bbi.2024.11.030, PubMed 39617069
Elevated levels of peripheral and central nervous system immune markers reflect innate immune dysregulation in autism spectrum disorder
Psychiatry Res, 342, 116245
DOI 10.1016/j.psychres.2024.116245, PubMed 39481220
Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain
Brain Behav Immun, 118, 287-299
DOI 10.1016/j.bbi.2024.03.014, PubMed 38461955
Longitudinal course of inflammatory-cognitive subgroups across first treatment severe mental illness and healthy controls
Psychol Med, 54 (12), 1-11 (in press)
DOI 10.1017/S003329172400206X, PubMed 39354711
Genome-wide determinants of mortality and motor progression in Parkinson's disease
NPJ Parkinsons Dis, 10 (1), 113
DOI 10.1038/s41531-024-00729-8, PubMed 38849413
Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders
Psychiatry Clin Neurosci, 78 (12), 783-791
DOI 10.1111/pcn.13742, PubMed 39301620
Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia
Mol Psychiatry, 29 (8), 2467-2477
DOI 10.1038/s41380-024-02513-9, PubMed 38503926
Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study
Nat Commun, 15 (1), 2655
DOI 10.1038/s41467-024-46817-4, PubMed 38531894
Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records
Age Ageing, 53 (2)
DOI 10.1093/ageing/afae006, PubMed 38342753
Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation
Schizophr Bull, 50 (2), 327-338
DOI 10.1093/schbul/sbad140, PubMed 37824720
Cellular adhesion molecules in drug-naïve and previously medicated patients with schizophrenia-spectrum disorders
Schizophr Res, 267, 223-229
DOI 10.1016/j.schres.2024.03.029, PubMed 38574562
History of childhood maltreatment associated with hospitalization or death due to COVID-19: a cohort study
BMC Med, 22 (1), 319
DOI 10.1186/s12916-024-03399-8, PubMed 39113083
Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage
Nat Genet, 56 (8), 1597-1603
DOI 10.1038/s41588-024-01839-y, PubMed 39039282
Genomic insights into the shared and distinct genetic architecture of cognitive function and schizophrenia
Sci Rep, 14 (1), 15356
DOI 10.1038/s41598-024-66085-y, PubMed 38961113
Divergent epigenetic responses to perinatal asphyxia in severe mental disorders
Transl Psychiatry, 14 (1), 16
DOI 10.1038/s41398-023-02709-7, PubMed 38191519
Sex differences in clinically diagnosed psychiatric disorders over the lifespan: a nationwide register-based study in Sweden
Lancet Reg Health Eur, 47, 101105
DOI 10.1016/j.lanepe.2024.101105, PubMed 39726722
Gut microbial diversity moderates polygenic risk of schizophrenia
Front Psychiatry, 15, 1275719
DOI 10.3389/fpsyt.2024.1275719, PubMed 38362027
Using brain structural neuroimaging measures to predict psychosis onset for individuals at clinical high-risk
Mol Psychiatry, 29 (5), 1465-1477
DOI 10.1038/s41380-024-02426-7, PubMed 38332374
Publications 2023
A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
Cancers (Basel), 15 (16)
DOI 10.3390/cancers15164124, PubMed 37627152
Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia
Biol Psychiatry, 95 (7), 687-698
DOI 10.1016/j.biopsych.2023.08.017, PubMed 37661009
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications
World Psychiatry, 22 (1), 4-24
DOI 10.1002/wps.21034, PubMed 36640404
Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals
EClinicalMedicine, 64, 102199
DOI 10.1016/j.eclinm.2023.102199, PubMed 37731936
Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood
Transl Psychiatry, 13 (1), 222
DOI 10.1038/s41398-023-02522-2, PubMed 37353490
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa
Transl Psychiatry, 13 (1), 291
DOI 10.1038/s41398-023-02585-1, PubMed 37658054
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
Int J Bipolar Disord, 11 (1), 22
DOI 10.1186/s40345-023-00303-w, PubMed 37347392
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Nat Genet, 55 (11), 1807-1819
DOI 10.1038/s41588-023-01520-w, PubMed 37798380
Puberty differentially predicts brain maturation in male and female youth: A longitudinal ABCD Study
Dev Cogn Neurosci, 61, 101261
DOI 10.1016/j.dcn.2023.101261, PubMed 37295068
Psychometric Properties and Diagnostic Associations of the Short-Form Community Assessment of Psychic Experiences in a Population-Based Sample of 29 021 Adult Men
Schizophr Bull, 49 (5), 1229-1238
DOI 10.1093/schbul/sbad074, PubMed 37262330
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura
Nat Genet, 55 (11), 1843-1853
DOI 10.1038/s41588-023-01538-0, PubMed 37884687
No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
Transl Psychiatry, 13 (1), 61
DOI 10.1038/s41398-023-02358-w, PubMed 36807331
Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
Biol Psychiatry, 95 (2), 147-160
DOI 10.1016/j.biopsych.2023.08.018, PubMed 37661008
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Nat Commun, 14 (1), 6172
DOI 10.1038/s41467-023-41180-2, PubMed 37794016
Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative
Focus (Am Psychiatr Publ), 21 (4), 444-452
DOI 10.1176/appi.focus.23021021, PubMed 38694997
Distributed genetic effects of the corpus callosum subregions suggest links to neuropsychiatric disorders and related traits
Acta Neuropsychiatr, 1-8 (in press)
DOI 10.1017/neu.2023.32, PubMed 37612147
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
Lancet Psychiatry, 10 (6), 441-451
DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 14 (1), 716
DOI 10.1038/s41467-023-36192-x, PubMed 36759603
Bounding the average causal effect in Mendelian randomisation studies with multiple proposed instruments: An application to prenatal alcohol exposure and attention deficit hyperactivity disorder
Paediatr Perinat Epidemiol, 37 (4), 326-337
DOI 10.1111/ppe.12951, PubMed 36722651
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Am J Psychiatry, 180 (10), 723-738
DOI 10.1176/appi.ajp.21121266, PubMed 37777856
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
JAMA Netw Open, 6 (5), e2313734
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Associations Between Clinical Insight and History of Severe Violence in Patients With Psychosis
Schizophr Bull Open, 4 (1), sgad011
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Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
Neurobiol Dis, 183, 106174
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Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression
Am J Psychiatry, 180 (12), 884-895
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Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
Psychoneuroendocrinology, 157, 106368
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Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
Nat Hum Behav, 7 (9), 1584-1600
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Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
BMC Psychiatry, 23 (1), 659
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Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability
Drug Alcohol Depend, 256, 111058
DOI 10.1016/j.drugalcdep.2023.111058, PubMed 38244365
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
Addict Biol, 28 (6), e13282
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Systemic immune profile in Prader-Willi syndrome: elevated matrix metalloproteinase and myeloperoxidase and reduced macrophage inhibitory factor
Orphanet J Rare Dis, 18 (1), 185
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Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Transl Psychiatry, 13 (1), 295
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Intra- and inter-individual cognitive variability in schizophrenia and bipolar spectrum disorder: an investigation across multiple cognitive domains
Schizophrenia (Heidelb), 9 (1), 89
DOI 10.1038/s41537-023-00414-4, PubMed 38110366
Etiologic Studies of Premenstrual Disorders Require Prospective Confirmation of Affective Cyclicity-Reply
JAMA Psychiatry, 80 (11), 1175-1176
DOI 10.1001/jamapsychiatry.2023.3290, PubMed 37703043
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
Schizophr Bull, 49 (6), 1654-1664
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Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders
JAMA Psychiatry, 80 (7), 738-742
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Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood?
Transl Psychiatry, 13 (1), 94
DOI 10.1038/s41398-023-02348-y, PubMed 36934099
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
Precision medicine in complex diseases-Molecular subgrouping for improved prediction and treatment stratification
J Intern Med, 294 (4), 378-396
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Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders
Exp Mol Med, 55 (6), 1193-1202
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Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
Brain, 146 (8), 3392-3403
DOI 10.1093/brain/awad038, PubMed 36757824
Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence
Nat Hum Behav, 7 (6), 1001-1017
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Brain-wide associations between white matter and age highlight the role of fornix microstructure in brain ageing
Hum Brain Mapp, 44 (10), 4101-4119
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Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants
Front Psychol, 14, 1117732
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Considerations on brain age predictions from repeatedly sampled data across time
Brain Behav, 13 (10), e3219
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Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants
Am J Psychiatry, 180 (9), 685-698
DOI 10.1176/appi.ajp.20220304, PubMed 37434504
Combining antidepressants and attention bias modification in primary health care (DEPTREAT): Protocol for a pragmatic randomized controlled trial
Contemp Clin Trials, 133, 107326
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Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
Proc Natl Acad Sci U S A, 120 (36), e2302720120
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Genetic architecture of brain age and its causal relations with brain and mental disorders
Mol Psychiatry, 28 (7), 3111-3120
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Elevated symptoms of depression and anxiety among family members and friends of critically ill COVID-19 patients - an observational study of five cohorts across four countries
Lancet Reg Health Eur, 33, 100733
DOI 10.1016/j.lanepe.2023.100733, PubMed 37953992
Mental Distress Among Norwegian Adults During the COVID-19 Pandemic: Predictors in Initial Response and Subsequent Trajectories
Int J Public Health, 68, 1606164
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Tobacco smoking related to childhood trauma mediated by cognitive control and impulsiveness in severe mental disorders
Schizophr Res, 261, 236-244
DOI 10.1016/j.schres.2023.09.041, PubMed 37806047
Visual processing deficits in patients with schizophrenia spectrum and bipolar disorders and associations with psychotic symptoms, and intellectual abilities
Heliyon, 9 (2), e13354
DOI 10.1016/j.heliyon.2023.e13354, PubMed 36825178
Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants
Psychol Med, 53 (14), 6743-6753
DOI 10.1017/S0033291723000223, PubMed 36846964
Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study
Schizophr Res, 255, 173-181
DOI 10.1016/j.schres.2023.03.020, PubMed 37001392
Telomere length and verbal learning in bipolar disorders
J Affect Disord, 339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
The Genetic Architecture of Amygdala Nuclei
Biol Psychiatry, 95 (1), 72-84
DOI 10.1016/j.biopsych.2023.06.022, PubMed 37391117
Brain-based gene expression of putative risk genes for anorexia nervosa
Mol Psychiatry, 28 (6), 2612-2619
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Thalamic nuclei volumes in schizophrenia and bipolar spectrum disorders - Associations with diagnosis and clinical characteristics
Schizophr Res, 256, 26-35
DOI 10.1016/j.schres.2023.04.008, PubMed 37126979
Erratum to "Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents" [Dev. Cogn. Neurosci. 56C (2022) 101132]
Dev Cogn Neurosci, 61, 101225
DOI 10.1016/j.dcn.2023.101225, PubMed 36870926
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
Psychiatry Res, 325, 115217
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Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3453
DOI 10.1038/s41467-023-38951-2, PubMed 37301908
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3923
DOI 10.1038/s41467-023-39492-4, PubMed 37400429
Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids
Mol Psychiatry, 28 (7), 3033-3043
DOI 10.1038/s41380-023-01944-0, PubMed 36653674
Genetic liability to schizophrenia and cardiac structure and function
Lancet Psychiatry, 10 (2), 72-73
DOI 10.1016/S2215-0366(23)00009-3, PubMed 36632819
Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
Biol Psychiatry, 95 (1), 62-71
DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology
Mol Psychiatry, 28 (11), 4924-4932
DOI 10.1038/s41380-023-02264-z, PubMed 37759039
Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers
Lancet Reg Health Eur, 29, 100621
DOI 10.1016/j.lanepe.2023.100621, PubMed 37265784
Mismatch negativity in schizophrenia spectrum and bipolar disorders: Group and sex differences and associations with symptom severity
Schizophr Res, 261, 80-93
DOI 10.1016/j.schres.2023.09.012, PubMed 37716205
Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures
Alzheimers Dement, 19 (11), 5151-5158
DOI 10.1002/alz.13112, PubMed 37132098
Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers
Eur Arch Psychiatry Clin Neurosci, 274 (5), 1223-1230
DOI 10.1007/s00406-023-01591-0, PubMed 37145175
Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank
BMC Psychiatry, 23 (1), 461
DOI 10.1186/s12888-023-04905-7, PubMed 37353766
Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors
Am J Psychiatry, 180 (11), 815-826
DOI 10.1176/appi.ajp.20220660, PubMed 37752828
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Proc Natl Acad Sci U S A, 120 (14), e2213880120
DOI 10.1073/pnas.2213880120, PubMed 36976765
Cardiometabolic health across menopausal years is linked to white matter hyperintensities up to a decade later
Front Glob Womens Health, 4, 1320640
DOI 10.3389/fgwh.2023.1320640, PubMed 38213741
Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience: A Review
JAMA Psychiatry, 80 (10), 1066-1074
DOI 10.1001/jamapsychiatry.2023.2996, PubMed 37610741
Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders
Nat Neurosci, 26 (9), 1613-1629
DOI 10.1038/s41593-023-01404-6, PubMed 37580620
COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark
Lancet Reg Health Eur, 35, 100756
DOI 10.1016/j.lanepe.2023.100756, PubMed 38115966
Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries
EClinicalMedicine, 61, 102063
DOI 10.1016/j.eclinm.2023.102063, PubMed 37425374
Patterns of pharmacotherapy for bipolar disorder: A GBC survey
Bipolar Disord, 26 (1), 22-32
DOI 10.1111/bdi.13366, PubMed 37463846
Relationship between function and structure in the visual cortex in healthy individuals and in patients with severe mental disorders
Psychiatry Res Neuroimaging, 332, 111633
DOI 10.1016/j.pscychresns.2023.111633, PubMed 37028226
Auditory Cortex Thickness Is Associated With N100 Amplitude in Schizophrenia Spectrum Disorders
Schizophr Bull Open, 4 (1), sgad015
DOI 10.1093/schizbullopen/sgad015, PubMed 38812720
Heritability Estimation of Cognitive Phenotypes in the ABCD Study® Using Mixed Models
Behav Genet, 53 (3), 169-188
DOI 10.1007/s10519-023-10141-2, PubMed 37024669
Maternal Fiber Intake During Pregnancy and Development of Attention-Deficit/Hyperactivity Disorder Symptoms Across Childhood: The Norwegian Mother, Father, and Child Cohort Study
Biol Psychiatry, 95 (9), 839-848
DOI 10.1016/j.biopsych.2023.12.017, PubMed 38142720
Genetic effects on the timing of parturition and links to fetal birth weight
Nat Genet, 55 (4), 559-567
DOI 10.1038/s41588-023-01343-9, PubMed 37012456
Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight
Nat Genet, 55 (7), 1250
DOI 10.1038/s41588-023-01412-z, PubMed 37165137
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
Schizophr Bull, 49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439
The effect of maternal BMI, smoking and alcohol on congenital heart diseases: a Mendelian randomisation study
BMC Med, 21 (1), 35
DOI 10.1186/s12916-023-02731-y, PubMed 36721200
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
Genome Med, 15 (1), 60
DOI 10.1186/s13073-023-01212-4, PubMed 37528461
Conduct disorder - a comprehensive exploration of comorbidity patterns, genetic and environmental risk factors
Psychiatry Res, 331, 115628
DOI 10.1016/j.psychres.2023.115628, PubMed 38029627
Risk of recurrent cardiovascular events in coronary artery disease patients with Type D personality
Front Psychol, 14, 1119146
DOI 10.3389/fpsyg.2023.1119146, PubMed 37057178
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
Transl Psychiatry, 13 (1), 147
DOI 10.1038/s41398-023-02442-1, PubMed 37147304
Differences in white blood cell proportions between schizophrenia cases and controls are influenced by medication and variations in time of day
Transl Psychiatry, 13 (1), 211
DOI 10.1038/s41398-023-02507-1, PubMed 37330513
Delineating disorder-general and disorder-specific dimensions of psychopathology from functional brain networks in a developmental clinical sample
Dev Cogn Neurosci, 62, 101271
DOI 10.1016/j.dcn.2023.101271, PubMed 37348146
Shared pattern of impaired social communication and cognitive ability in the youth brain across diagnostic boundaries
Dev Cogn Neurosci, 60, 101219
DOI 10.1016/j.dcn.2023.101219, PubMed 36812678
TMEM161B modulates radial glial scaffolding in neocortical development
Proc Natl Acad Sci U S A, 120 (4), e2209983120
DOI 10.1073/pnas.2209983120, PubMed 36669109
Reaction Time Variability in Children Is Specifically Associated With Attention Problems and Regional White Matter Microstructure
Biol Psychiatry Cogn Neurosci Neuroimaging, 8 (8), 832-840
DOI 10.1016/j.bpsc.2023.03.010, PubMed 37003411
Assessing the Longitudinal Associations Between Decision-Making Processes and Attention Problems in Early Adolescence
Res Child Adolesc Psychopathol, 52 (5), 803-817
DOI 10.1007/s10802-023-01148-8, PubMed 38103132
Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability
Mol Psychiatry, 28 (9), 4011-4019
DOI 10.1038/s41380-023-02292-9, PubMed 37864076
Associations between health behaviours, fertility and reproductive outcomes: triangulation of evidence in the Norwegian Mother, Father and Child Cohort Study (MoBa)
BMC Med, 21 (1), 125
DOI 10.1186/s12916-023-02831-9, PubMed 37013617
The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development
Transl Psychiatry, 13 (1), 343
DOI 10.1038/s41398-023-02639-4, PubMed 37938559
Baseline long-term potentiation-like cortical plasticity is associated with longitudinal cortical thinning in healthy adults and in adults with bipolar disorder type II
Eur J Neurosci, 58 (3), 2824-2837
DOI 10.1111/ejn.16038, PubMed 37163975
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
Sci Rep, 13 (1), 13845
DOI 10.1038/s41598-023-40310-6, PubMed 37620394
Publications 2022
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response
Schizophr Bull, 48 (1), 190-198
DOI 10.1093/schbul/sbab092, PubMed 34357384
Lifetime and point prevalence of psychotic symptoms in adults with bipolar disorders: a systematic review and meta-analysis
Psychol Med, 52 (13), 2413-2425
DOI 10.1017/S003329172200201X, PubMed 36016504
Herpes simplex virus 1 infection on grey matter and general intelligence in severe mental illness
Transl Psychiatry, 12 (1), 276
DOI 10.1038/s41398-022-02044-3, PubMed 35821107
Cytomegalovirus Infection Associated with Smaller Total Cortical Surface Area in Schizophrenia Spectrum Disorders
Schizophr Bull, 48 (5), 1164-1173
DOI 10.1093/schbul/sbac036, PubMed 35388401
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
Brain, 145 (1), 142-153
DOI 10.1093/brain/awab267, PubMed 34273149
Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders
Nat Commun, 13 (1), 3436
DOI 10.1038/s41467-022-31086-w, PubMed 35705537
Childhood temperamental, emotional, and behavioral characteristics associated with mood and anxiety disorders in adolescence: A prospective study
Acta Psychiatr Scand, 147 (2), 217-228
DOI 10.1111/acps.13522, PubMed 36398468
Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis
Transl Psychiatry, 12 (1), 297
DOI 10.1038/s41398-022-02057-y, PubMed 35882855
In vivo white matter microstructure in adolescents with early-onset psychosis: a multi-site mega-analysis
Mol Psychiatry, 28 (3), 1159-1169
DOI 10.1038/s41380-022-01901-3, PubMed 36510004
Association between polarity of first episode and solar insolation in bipolar I disorder
J Psychosom Res, 160, 110982
DOI 10.1016/j.jpsychores.2022.110982, PubMed 35932492
Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults
Neuroimage Clin, 33, 102949
DOI 10.1016/j.nicl.2022.102949, PubMed 35114636
Psychopathy subdomains in violent offenders with and without a psychotic disorder
Nord J Psychiatry, 77 (4), 393-402
DOI 10.1080/08039488.2022.2128869, PubMed 36260740
New insights into the genetic etiology of Alzheimer's disease and related dementias
Nat Genet, 54 (4), 412-436
DOI 10.1038/s41588-022-01024-z, PubMed 35379992
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J. Affect. Disord., 297, 1032-1039
DOI 10.1016/j.jad.2021.08.135
Developing "MinDag" - an app to capture symptom variation and illness mechanisms in bipolar disorder
Front Med Technol, 4, 910533
DOI 10.3389/fmedt.2022.910533, PubMed 35935144
Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach
Drug Alcohol Depend, 234, 109430
DOI 10.1016/j.drugalcdep.2022.109430, PubMed 35367939
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Nat Neurosci, 25 (4), 421-432
DOI 10.1038/s41593-022-01042-4, PubMed 35383335
Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative
Bipolar Disord, 24 (7), 709-719
DOI 10.1111/bdi.13208, PubMed 35322518
Cytomegalovirus infection associated with lower IQ in adolescent patients with schizophrenia spectrum disorders: A preliminary report
J Psychiatr Res, 151, 571-574
DOI 10.1016/j.jpsychires.2022.05.036, PubMed 35636034
A population-wide gene-environment interaction study on how genes, schools, and residential areas shape achievement
NPJ Sci Learn, 7 (1), 29
DOI 10.1038/s41539-022-00145-8, PubMed 36302785
How interactions between ADHD and schools affect educational achievement: a family-based genetically sensitive study
J Child Psychol Psychiatry, 63 (10), 1174-1185
DOI 10.1111/jcpp.13656, PubMed 35789088
Genome-Transcriptome-Functional Connectivity-Cognition Link Differentiates Schizophrenia From Bipolar Disorder
Schizophr Bull, 48 (6), 1306-1317
DOI 10.1093/schbul/sbac088, PubMed 35988022
Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood
Mol Psychiatry, 27 (12), 5167-5176
DOI 10.1038/s41380-022-01751-z, PubMed 36100668
Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings
Psychiatry Clin Neurosci, 76 (5), 140-161
DOI 10.1111/pcn.13337, PubMed 35119167
Associations Between Depression and Cardiometabolic Health: A 27-Year Longitudinal Study - Corrigendum
Psychol Med, 52 (14), 3018
DOI 10.1017/S0033291722003105, PubMed 36177891
On the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families
J Child Psychol Psychiatry, 63 (10), 1186-1195
DOI 10.1111/jcpp.13654, PubMed 35778910
Composite immune marker scores associated with severe mental disorders and illness course
Brain Behav Immun Health, 24, 100483
DOI 10.1016/j.bbih.2022.100483, PubMed 35856063
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169
Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain
Nat Commun, 13 (1), 2423
DOI 10.1038/s41467-022-30110-3, PubMed 35505052
Associations between brain imaging and polygenic scores of mental health and educational attainment in children aged 9-11
Neuroimage, 263, 119611
DOI 10.1016/j.neuroimage.2022.119611, PubMed 36070838
Ethical considerations for precision psychiatry: A roadmap for research and clinical practice
Eur Neuropsychopharmacol, 63, 17-34
DOI 10.1016/j.euroneuro.2022.08.001, PubMed 36041245
Lifetime Cannabis Use Is Not Associated With Negative Beliefs About Medication in Patients With First Treatment Psychosis
Front Psychiatry, 13, 824051
DOI 10.3389/fpsyt.2022.824051, PubMed 35422717
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Nat Commun, 13 (1), 4682
DOI 10.1038/s41467-022-32420-y, PubMed 35948562
Associations Between Pregnancy-Related Predisposing Factors for Offspring Neurodevelopmental Conditions and Parental Genetic Liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa)
JAMA Psychiatry, 79 (8), 799-810
DOI 10.1001/jamapsychiatry.2022.1728, PubMed 35793100
Characterization of the genetic architecture of infant and early childhood body mass index
Nat Metab, 4 (3), 344-358
DOI 10.1038/s42255-022-00549-1, PubMed 35315439
Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Fertil Steril, 118 (1), 180-190
DOI 10.1016/j.fertnstert.2022.04.001, PubMed 35562204
Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders
Nat Commun, 13 (1), 6851
DOI 10.1038/s41467-022-34367-6, PubMed 36369423
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
Am J Psychiatry, 179 (11), 833-843
DOI 10.1176/appi.ajp.21101051, PubMed 36069018
The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis
Am J Med Genet B Neuropsychiatr Genet, 189 (6), 207-218
DOI 10.1002/ajmg.b.32907, PubMed 35841185
Interleukin-18 signaling system links to agitation in severe mental disorders
Psychoneuroendocrinology, 140, 105721
DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151
Polygenic resilience scores capture protective genetic effects for Alzheimer's disease
Transl Psychiatry, 12 (1), 296
DOI 10.1038/s41398-022-02055-0, PubMed 35879306
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Nat Genet, 54 (5), 581-592
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Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study
Elife, 11
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Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
Prostate Cancer Prostatic Dis, 25 (4), 755-761
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Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study
Front Psychiatry, 13, 813256
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Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings
Neuropsychopharmacology, 47 (11), 1883-1891
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Limited evidence for a moderating effect of HIV status on brain age in heavy episodic drinkers
J Neurovirol, 28 (3), 383-391
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Birth order differences in education originate in postnatal environments
PNAS Nexus, 1 (2), pgac051
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Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms
J Am Acad Child Adolesc Psychiatry, 61 (7), 934-945
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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers
Acta Neuropathol, 144 (5), 821-842
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Correction to: Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1198
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Sex differences in antipsychotic-related triglyceride levels are associated with metabolic hormone differences in patients with severe mental disorders
Schizophr Res, 243, 55-63
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Sex-specific associations between metabolic hormones, severe mental disorders and antipsychotic treatment
Psychoneuroendocrinology, 146, 105927
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Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores
Biol Psychiatry, 93 (2), 149-156
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Closing the life-cycle of normative modeling using federated hierarchical Bayesian regression
PLoS One, 17 (12), e0278776
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Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth
Biol Psychiatry Glob Open Sci, 3 (2), 255-263
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Study protocol for "MDMA-assisted therapy as a treatment for major depressive disorder: A proof of principle study"
Front Psychiatry, 13, 954388
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Metabolite Profiling of Clozapine in Patients Switching Versus Maintaining Treatment: A Retrospective Pilot Study
J Clin Psychopharmacol, 42 (5), 470-474
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Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease
JAMA Neurol, 79 (7), 652-663
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Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits
Clin Transl Sci, 16 (1), 62-72
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Deep neural networks learn general and clinically relevant representations of the ageing brain
Neuroimage, 256, 119210
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Generalization of cortical MOSTest genome-wide associations within and across samples
Neuroimage, 263, 119632
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Functional connectivity directionality between large-scale resting-state networks across typical and non-typical trajectories in children and adolescence
PLoS One, 17 (12), e0276221
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An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD
Transl Psychiatry, 12 (1), 177
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Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study
Lancet Public Health, 7 (5), e406-e416
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Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases
Science, 375 (6580), 522-528
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Strategies and foundations for scientific discovery in longitudinal studies of bipolar disorder
Bipolar Disord, 24 (5), 499-508
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Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
J Alzheimers Dis, 88 (4), 1533-1544
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Negative Symptom Domains Are Associated With Verbal Learning in Adolescents With Early Onset Psychosis
Front Psychiatry, 12, 825681
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A comparison of intracranial volume estimation methods and their cross-sectional and longitudinal associations with age
Hum Brain Mapp, 43 (15), 4620-4639
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Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents
Dev Cogn Neurosci, 56, 101132
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Phenotype-informed polygenic risk scores are associated with worse outcome in individuals at risk of Alzheimer's disease
Alzheimers Dement (Amst), 14 (1), e12350
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Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia
JAMA Psychiatry, 79 (3), 260-269
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Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology
Commun Biol, 5 (1), 1024
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Virtual Ontogeny of Cortical Growth Preceding Mental Illness
Biol Psychiatry, 92 (4), 299-313
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Computational Modeling of the n-Back Task in the ABCD Study: Associations of Drift Diffusion Model Parameters to Polygenic Scores of Mental Disorders and Cardiometabolic Diseases
Biol Psychiatry Cogn Neurosci Neuroimaging, 8 (3), 290-299
DOI 10.1016/j.bpsc.2022.03.012, PubMed 35427796
Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study
Mol Psychiatry, 28 (4), 1731-1738
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The co-occurrence of motor and language impairments in children evaluated for autism spectrum disorder. An explorative study from Norway
Res Dev Disabil, 127, 104256
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Quality of clinical management of cardiometabolic risk factors in patients with severe mental illness in a specialist mental health care setting
Nord J Psychiatry, 76 (8), 602-609
DOI 10.1080/08039488.2022.2039288, PubMed 35200088
Oxytocin receptor expression patterns in the human brain across development
Neuropsychopharmacology, 47 (8), 1550-1560
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Clinical and cortical similarities identified between bipolar disorder I and schizophrenia: A multivariate approach
Front Hum Neurosci, 16, 1001692
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Cardiovascular disease risk in people with severe mental disorders: an update and call for action
Curr Opin Psychiatry, 35 (4), 277-284
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Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis, 81 (8), 1085-1095
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Theory of mind in schizophrenia: a comparison of subgroups with low and high IQ
Nord J Psychiatry, 77 (4), 329-335
DOI 10.1080/08039488.2022.2106512, PubMed 35916656
Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women
Neuroimage Clin, 36, 103239
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Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530
Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium
Schizophr Res, 250, 1-9
DOI 10.1016/j.schres.2022.09.009, PubMed 36242784
Schizophrenia: genetic insights with clinical potential
Nat Rev Neurol, 18 (3), 129-130
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Borderline personality disorder and the big five: molecular genetic analyses indicate shared genetic architecture with neuroticism and openness
Transl Psychiatry, 12 (1), 153
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Sex- and age-specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort
Hum Brain Mapp, 43 (12), 3759-3774
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Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
Mol Psychiatry, 28 (3), 1284-1292
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The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analyses
J Cardiovasc Dev Dis, 9 (8)
DOI 10.3390/jcdd9080237, PubMed 36005401
The age of violence: Mapping brain age in psychosis and psychopathy
Neuroimage Clin, 36, 103181
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Shared genetic loci between depression and cardiometabolic traits
PLoS Genet, 18 (5), e1010161
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Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder
J Autism Dev Disord, 53 (10), 3847-3859
DOI 10.1007/s10803-022-05629-5, PubMed 35838825
Modeling assortative mating and genetic similarities between partners, siblings, and in-laws
Nat Commun, 13 (1), 1108
DOI 10.1038/s41467-022-28774-y, PubMed 35233010
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 604 (7906), 502-508
DOI 10.1038/s41586-022-04434-5, PubMed 35396580
Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations
Int J Epidemiol, 51 (3), e108-e122
DOI 10.1093/ije/dyab234, PubMed 35020900
Editorial: Cross-disorder Genetics in Neuropsychiatry
Front Neurosci, 16, 826300
DOI 10.3389/fnins.2022.826300, PubMed 35221906
The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
Commun Biol, 5 (1), 1271
DOI 10.1038/s42003-022-04237-4, PubMed 36402844
Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
Biol Psychiatry, 92 (4), 291-298
DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
Transl Psychiatry, 12 (1), 38
DOI 10.1038/s41398-022-01811-6, PubMed 35082268
Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 54 (7), 1062
DOI 10.1038/s41588-022-01126-8, PubMed 35726068
Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex
Nat Commun, 13 (1), 7945
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The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health
Psychoneuroendocrinology, 144, 105875
DOI 10.1016/j.psyneuen.2022.105875, PubMed 35939863
Retrospectively assessed childhood trauma experiences are associated with illness severity in mental disorders adjusted for symptom state
Psychiatry Res, 320, 115045
DOI 10.1016/j.psychres.2022.115045, PubMed 36621206
Publications 2021
Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group
Biol Psychiatry, 91 (6), 582-592
DOI 10.1016/j.biopsych.2021.09.008, PubMed 34809987
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
Brain Behav Immun, 94, 235-244
DOI 10.1016/j.bbi.2021.01.037, PubMed 33571628
Cytomegalovirus infection associated with smaller dentate gyrus in men with severe mental illness
Brain Behav Immun, 96, 54-62
DOI 10.1016/j.bbi.2021.05.009, PubMed 34010712
Lower plasma total tau in adolescent psychosis: Involvement of the orbitofrontal cortex
J Psychiatr Res, 144, 255-261
DOI 10.1016/j.jpsychires.2021.10.031, PubMed 34700214
Cytomegalovirus infection and IQ in patients with severe mental illness and healthy individuals
Psychiatry Res, 300, 113929
DOI 10.1016/j.psychres.2021.113929, PubMed 33866186
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 53 (4), 1479-1488
DOI 10.1017/S0033291721003056, PubMed 35387700
Risk and protective factors for mental disorders beyond genetics: an evidence-based atlas
World Psychiatry, 20 (3), 417-436
DOI 10.1002/wps.20894, PubMed 34505386
Early manifestations of genetic risk for neurodevelopmental disorders
J Child Psychol Psychiatry, 63 (7), 810-819
DOI 10.1111/jcpp.13528, PubMed 34605010
Genetic loci shared between major depression and intelligence with mixed directions of effect
Nat Hum Behav, 5 (6), 795-801
DOI 10.1038/s41562-020-01031-2, PubMed 33462475
In Vivo Amygdala Nuclei Volumes in Schizophrenia and Bipolar Disorders
Schizophr Bull, 47 (5), 1431-1441
DOI 10.1093/schbul/sbaa192, PubMed 33479754
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
Int J Bipolar Disord, 9 (1), 26
DOI 10.1186/s40345-021-00231-7, PubMed 34467430
Cardiometabolic risk factors associated with brain age and accelerate brain ageing
Hum Brain Mapp, 43 (2), 700-720
DOI 10.1002/hbm.25680, PubMed 34626047
Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending
Psychiatry Res Neuroimaging, 319, 111416
DOI 10.1016/j.pscychresns.2021.111416, PubMed 34847406
Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms
BMC Psychiatry, 21 (1), 527
DOI 10.1186/s12888-021-03522-6, PubMed 34702245
Elevated levels of soluble urokinase plasminogen activator receptor as a low-grade inflammation marker in schizophrenia: A case-control study
Schizophr Res, 228, 190-192
DOI 10.1016/j.schres.2020.11.051, PubMed 33450603
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J Affect Disord, 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Biol Psychiatry, 91 (1), 102-117
DOI 10.1016/j.biopsych.2021.02.972, PubMed 34099189
Sparse deep neural networks on imaging genetics for schizophrenia case-control classification
Hum Brain Mapp, 42 (8), 2556-2568
DOI 10.1002/hbm.25387, PubMed 33724588
Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness
JAMA Psychiatry, 78 (9), 1020-1030
DOI 10.1001/jamapsychiatry.2021.1435, PubMed 34160554
Prominent health problems, socioeconomic deprivation, and higher brain age in lonely and isolated individuals: A population-based study
Behav Brain Res, 414, 113510
DOI 10.1016/j.bbr.2021.113510, PubMed 34358570
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 12 (1), 3417
DOI 10.1038/s41467-021-22491-8, PubMed 34099642
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
Mol Psychiatry, 26 (10), 5797-5811
DOI 10.1038/s41380-021-01152-8, PubMed 34112972
Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years
Hum Brain Mapp, 43 (1), 452-469
DOI 10.1002/hbm.25320, PubMed 33570244
Associations between depression and cardiometabolic health: A 27-year longitudinal study
Psychol Med, 52 (14), 3007-3017
DOI 10.1017/S003329172000505X, PubMed 33431106
The genetic architecture of the human thalamus and its overlap with ten common brain disorders
Nat Commun, 12 (1), 2909
DOI 10.1038/s41467-021-23175-z, PubMed 34006833
Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis
JAMA Psychiatry, 78 (7), 753-766
DOI 10.1001/jamapsychiatry.2021.0638, PubMed 33950164
Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study
Pharmacogenomics J, 21 (5), 574-585
DOI 10.1038/s41397-021-00234-8, PubMed 33824429
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years
Hum Brain Mapp, 43 (1), 431-451
DOI 10.1002/hbm.25364, PubMed 33595143
Sex-Specific Effect of Serum Lipids and Body Mass Index on Psychotic Symptoms, a Cross-Sectional Study of First-Episode Psychosis Patients
Front Psychiatry, 12, 723158
DOI 10.3389/fpsyt.2021.723158, PubMed 34744818
Population-based body-brain mapping links brain morphology with anthropometrics and body composition
Transl Psychiatry, 11 (1), 295
DOI 10.1038/s41398-021-01414-7, PubMed 34006848
A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium
Hum Brain Mapp, 43 (1), 352-372
DOI 10.1002/hbm.25625, PubMed 34498337
Genetic Liability for Schizophrenia and Childhood Psychopathology in the General Population
Schizophr Bull, 47 (4), 1179-1189
DOI 10.1093/schbul/sbaa193, PubMed 33561255
Developmental milestones in early childhood and genetic liability to neurodevelopmental disorders
Psychol Med, 53 (5), 1750-1758
DOI 10.1017/S0033291721003330, PubMed 37310338
Interplay between the Genetics of Personality Traits, severe Psychiatric Disorders, and COVID-19 Host Genetics in the Susceptibility to SARS-CoV-2 Infection - ADDENDUM
BJPsych Open, 7 (6), e206
DOI 10.1192/bjo.2021.1037, PubMed 34789355
Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infection
BJPsych Open, 7 (6), e188
DOI 10.1192/bjo.2021.1030, PubMed 34659794
Aberrant default mode connectivity in adolescents with early-onset psychosis: A resting state fMRI study
Neuroimage Clin, 33, 102881
DOI 10.1016/j.nicl.2021.102881, PubMed 34883402
Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
Transl Psychiatry, 11 (1), 466
DOI 10.1038/s41398-021-01576-4, PubMed 34497263
The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity
Genetics, 217 (3)
DOI 10.1093/genetics/iyaa046, PubMed 33789345
Erratum to: The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity
Genetics, 218 (2)
DOI 10.1093/genetics/iyab064, PubMed 34167151
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
Nat Commun, 12 (1), 1236
DOI 10.1038/s41467-021-21287-0, PubMed 33623038
Common genetic and clinical risk factors: association with fatal prostate cancer in the Cohort of Swedish Men
Prostate Cancer Prostatic Dis, 24 (3), 845-851
DOI 10.1038/s41391-021-00341-4, PubMed 33723363
Maternal and offspring genetic risk score analyses of fetal alcohol exposure and attention-deficit hyperactivity disorder risk in offspring
Alcohol Clin Exp Res, 45 (10), 2090-2102
DOI 10.1111/acer.14692, PubMed 34486127
Multivariate alterations in insula - Medial prefrontal cortex linked to genetics in 12q24 in schizophrenia
Psychiatry Res, 306, 114237
DOI 10.1016/j.psychres.2021.114237, PubMed 34655926
Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1138-1146
DOI 10.1038/s41431-021-00966-y, PubMed 34776508
Characterisation of age and polarity at onset in bipolar disorder
Br J Psychiatry, 219 (6), 659-669
DOI 10.1192/bjp.2021.102, PubMed 35048876
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
Prostate Cancer Prostatic Dis, 24 (2), 532-541
DOI 10.1038/s41391-020-00311-2, PubMed 33420416
Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24
Prostate Cancer Prostatic Dis, 25 (2), 229-237
DOI 10.1038/s41391-021-00403-7, PubMed 34127801
DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis - A narrative review from the ECNP bipolar disorders network
Eur Neuropsychopharmacol, 47, 54-61
DOI 10.1016/j.euroneuro.2021.01.097, PubMed 33541809
Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
Prog Neuropsychopharmacol Biol Psychiatry, 112, 110408
DOI 10.1016/j.pnpbp.2021.110408, PubMed 34320404
Ketamine for depression - evidence and proposals for practice
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0480, PubMed 34726043
[Not Available]
Tidsskr Nor Laegeforen, 141
DOI 10.4045/tidsskr.21.0760, PubMed 34758606
Absolute and Dose-Adjusted Serum Concentrations of Clozapine in Patients Switching vs. Maintaining Treatment: An Observational Study of 1979 Patients
CNS Drugs, 35 (9), 999-1008
DOI 10.1007/s40263-021-00847-4, PubMed 34417726
Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
Neuropsychopharmacology, 46 (10), 1788-1801
DOI 10.1038/s41386-021-01023-4, PubMed 34035472
The association between bullying and eating disorders: A case-control study
Int J Eat Disord, 54 (8), 1405-1414
DOI 10.1002/eat.23522, PubMed 33942329
Stressful life events among individuals with a history of eating disorders: a case-control comparison
BMC Psychiatry, 21 (1), 501
DOI 10.1186/s12888-021-03499-2, PubMed 34645394
Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study
Bipolar Disord, 23 (8), 821-831
DOI 10.1111/bdi.13078, PubMed 33797828
Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms
Neuroimage Clin, 33, 102921
DOI 10.1016/j.nicl.2021.102921, PubMed 34959052
Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control
Eur Psychiatry, 64 (1), e24
DOI 10.1192/j.eurpsy.2021.14, PubMed 33775258
Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
Biol Psychiatry, 91 (7), 626-636
DOI 10.1016/j.biopsych.2021.09.020, PubMed 34865855
Corrigendum to "Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action [European Neuropsychopharmacology (2020) 36, 121-136]"
Eur Neuropsychopharmacol, 44, 121-122
DOI 10.1016/j.euroneuro.2021.01.001, PubMed 33495109
The genetic structure of Norway
Eur J Hum Genet, 29 (11), 1710-1718
DOI 10.1038/s41431-021-00899-6, PubMed 34002043
Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals
Bipolar Disord, 24 (5), 509-520
DOI 10.1111/bdi.13172, PubMed 34894200
Diphtheria And Tetanus Vaccination History Is Associated With Lower Odds of COVID-19 Hospitalization
Front Immunol, 12, 749264
DOI 10.3389/fimmu.2021.749264, PubMed 34691063
Genetic Overlap Between Alzheimer's Disease and Depression Mapped Onto the Brain
Front Neurosci, 15, 653130
DOI 10.3389/fnins.2021.653130, PubMed 34290577
A review of systems biology research of anxiety disorders
Braz J Psychiatry, 43 (4), 414-423
DOI 10.1590/1516-4446-2020-1090, PubMed 33053074
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nat Genet, 53 (6), 817-829
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Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Biol Psychiatry, 91 (3), 313-327
DOI 10.1016/j.biopsych.2021.05.029, PubMed 34861974
Multisite reproducibility and test-retest reliability of the T1w/T2w-ratio: A comparison of processing methods
Neuroimage, 245, 118709
DOI 10.1016/j.neuroimage.2021.118709, PubMed 34848300
New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro- and microstructural MRI findings
Prog Neurobiol, 204, 102109
DOI 10.1016/j.pneurobio.2021.102109, PubMed 34147583
Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes
Biol Psychiatry, 90 (9), 621-631
DOI 10.1016/j.biopsych.2021.07.007, PubMed 34482950
Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank
Psychol Med, 52 (15), 1-11 (in press)
DOI 10.1017/S0033291721000179, PubMed 33653435
Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
Mol Psychiatry, 26 (11), 6789-6805
DOI 10.1038/s41380-021-01164-4, PubMed 34075196
Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium
J Psychiatr Res, 137, 215-224
DOI 10.1016/j.jpsychires.2021.02.027, PubMed 33691233
Genetic Stratification of Age-Dependent Parkinson's Disease Risk by Polygenic Hazard Score
Mov Disord, 37 (1), 62-69
DOI 10.1002/mds.28808, PubMed 34612543
Identification of pleiotropy at the gene level between psychiatric disorders and related traits
Transl Psychiatry, 11 (1), 410
DOI 10.1038/s41398-021-01530-4, PubMed 34326310
All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
Front Cell Neurosci, 15, 671549
DOI 10.3389/fncel.2021.671549, PubMed 34122014
Structural and Pragmatic Language Impairments in Children Evaluated for Autism Spectrum Disorder (ASD)
J Autism Dev Disord, 53 (2), 701-719
DOI 10.1007/s10803-020-04853-1, PubMed 33515169
Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review
Eur Neuropsychopharmacol, 54, 90-99
DOI 10.1016/j.euroneuro.2021.09.001, PubMed 34607722
Adiponectin Is Related to Cardiovascular Risk in Severe Mental Illness Independent of Antipsychotic Treatment
Front Psychiatry, 12, 623192
DOI 10.3389/fpsyt.2021.623192, PubMed 34122163
Phenotypically independent profiles relevant to mental health are genetically correlated
Transl Psychiatry, 11 (1), 202
DOI 10.1038/s41398-021-01313-x, PubMed 33795632
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Transl Psychiatry, 11 (1), 407
DOI 10.1038/s41398-021-01527-z, PubMed 34301917
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458
Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology
Neuroimage, 244, 118603
DOI 10.1016/j.neuroimage.2021.118603, PubMed 34560273
Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment and Alzheimer's disease with dementia
Int Psychogeriatr, 33 (11), 1217-1228
DOI 10.1017/S1041610221000934, PubMed 34399870
Polygenic risk scores in psychiatry - Large potential but still limited clinical utility
Eur Neuropsychopharmacol, 51, 68-70
DOI 10.1016/j.euroneuro.2021.05.007, PubMed 34091254
Cognitive impairment profile in adolescent early-onset psychosis using the MATRICS Battery: Age and sex effects
Neuropsychology, 35 (3), 300-309
DOI 10.1037/neu0000723, PubMed 33970663
Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity
Brain Behav, 11 (8), e02188
DOI 10.1002/brb3.2188, PubMed 34291596
Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis
Front Neurosci, 15, 678503
DOI 10.3389/fnins.2021.678503, PubMed 34248484
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
Transl Psychiatry, 11 (1), 554
DOI 10.1038/s41398-021-01681-4, PubMed 34716291
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
Hum Brain Mapp, 43 (1), 300-328
DOI 10.1002/hbm.25354, PubMed 33615640
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
Transl Psychiatry, 11 (1), 182
DOI 10.1038/s41398-021-01213-0, PubMed 33753722
ENIGMA-Sleep: Challenges, opportunities, and the road map
J Sleep Res, 30 (6), e13347
DOI 10.1111/jsr.13347, PubMed 33913199
Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors
Transl Psychiatry, 11 (1), 368
DOI 10.1038/s41398-021-01466-9, PubMed 34226488
Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder
Schizophr Bull, 47 (6), 1751-1760
DOI 10.1093/schbul/sbab049, PubMed 33963856
The genetic architecture of human cortical folding
Sci Adv, 7 (51), eabj9446
DOI 10.1126/sciadv.abj9446, PubMed 34910505
The factor structure of social cognition in schizophrenia: Weak evidence for separable domains
Schizophr Res Cogn, 26, 100208
DOI 10.1016/j.scog.2021.100208, PubMed 34430229
Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes
Front Aging Neurosci, 13, 674318
DOI 10.3389/fnagi.2021.674318, PubMed 34122051
Causal association of cognitive reserve on Alzheimer's disease with putative sex difference
Alzheimers Dement (Amst), 13 (1), e12270
DOI 10.1002/dad2.12270, PubMed 35005200
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Biol Psychiatry Glob Open Sci, 2 (4), 368-378
DOI 10.1016/j.bpsgos.2021.09.001, PubMed 36324647
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (9), 1276-1282
DOI 10.1038/s41588-021-00921-z, PubMed 34493870
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (12), 1722
DOI 10.1038/s41588-021-00977-x, PubMed 34773122
12-year prediction of mild cognitive impairment aided by Alzheimer's brain signatures at mean age 56
Brain Commun, 3 (3), fcab167
DOI 10.1093/braincomms/fcab167, PubMed 34396116
Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank
Transl Psychiatry, 11 (1), 599
DOI 10.1038/s41398-021-01725-9, PubMed 34824196
Psychometric properties of the Norwegian version of the Patient Health Questionnaire-9 (PHQ-9) in a large female sample of adults with and without eating disorders
BMC Psychiatry, 21 (1), 6
DOI 10.1186/s12888-020-03013-0, PubMed 33402149
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
Addiction, 117 (3), 600-610
DOI 10.1111/add.15680, PubMed 34472679
Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder
Hum Brain Mapp, 42 (8), 2546-2555
DOI 10.1002/hbm.25386, PubMed 33638594
Association of Birth Asphyxia With Regional White Matter Abnormalities Among Patients With Schizophrenia and Bipolar Disorders
JAMA Netw Open, 4 (12), e2139759
DOI 10.1001/jamanetworkopen.2021.39759, PubMed 34928356
Significant association between intracranial volume and verbal intellectual abilities in patients with schizophrenia and a history of birth asphyxia
Psychol Med, 52 (15), 1-10 (in press)
DOI 10.1017/S0033291721000489, PubMed 33750510
Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders
JAMA Psychiatry, 78 (1), 47-63
DOI 10.1001/jamapsychiatry.2020.2694, PubMed 32857118
Gut microbial biomarkers for the treatment response in first-episode, drug-naïve schizophrenia: a 24-week follow-up study
Transl Psychiatry, 11 (1), 422
DOI 10.1038/s41398-021-01531-3, PubMed 34376634
Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders
World J Biol Psychiatry, 22 (8), 637-645
DOI 10.1080/15622975.2021.1907707, PubMed 33779484
Publications 2020
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun, 87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
The effects of cognitive abilities and task demands on tonic and phasic pupil sizes
Biol Psychol, 156, 107945
DOI 10.1016/j.biopsycho.2020.107945, PubMed 32889001
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
JAMA Psychiatry, 77 (5), 503-512
DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414
Exploring white matter microstructure and the impact of antipsychotics in adolescent-onset psychosis
PLoS One, 15 (5), e0233684
DOI 10.1371/journal.pone.0233684, PubMed 32470000
White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction
Neuroimage, 224, 117441
DOI 10.1016/j.neuroimage.2020.117441, PubMed 33039618
Heart rate variability is associated with disease severity in psychosis spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 111, 110108
DOI 10.1016/j.pnpbp.2020.110108, PubMed 32946948
How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)
BMC Med, 18 (1), 284
DOI 10.1186/s12916-020-01760-1, PubMed 33106172
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 56-82
DOI 10.1002/hbm.25098, PubMed 32725849
Genetic control of variability in subcortical and intracranial volumes
Mol Psychiatry, 26 (8), 3876-3883
DOI 10.1038/s41380-020-0664-1, PubMed 32047264
Genome-wide association study identifies 48 common genetic variants associated with handedness
Nat Hum Behav, 5 (1), 59-70
DOI 10.1038/s41562-020-00956-y, PubMed 32989287
Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder
Hum Brain Mapp, 43 (1), 414-430
DOI 10.1002/hbm.25206, PubMed 33027543
Exploring the Effects of an Acute Dose of Antipsychotic Medication on Motivation-mediated BOLD Activity Using fMRI and a Perceptual Decision-making Task
Neuroscience, 440, 146-159
DOI 10.1016/j.neuroscience.2020.05.035, PubMed 32473275
Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study
BMC Psychiatry, 20 (1), 582
DOI 10.1186/s12888-020-02968-4, PubMed 33287748
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
Transl Psychiatry, 10 (1), 416
DOI 10.1038/s41398-020-01094-9, PubMed 33257657
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease
Brain, 143 (7), 2272-2280
DOI 10.1093/brain/awaa164, PubMed 32591829
Social Perception Predicts Awareness of Illness in Persons With Schizophrenia
J Nerv Ment Dis, 208 (9), 701-705
DOI 10.1097/NMD.0000000000001185, PubMed 32433201
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296
Intracranial and subcortical volumes in adolescents with early-onset psychosis: A multisite mega-analysis from the ENIGMA consortium
Hum Brain Mapp, 43 (1), 373-384
DOI 10.1002/hbm.25212, PubMed 33017498
Computationally efficient familywise error rate control in genome-wide association studies using score tests for generalized linear models
Scand. J. Stat., 47 (4), 1090-1113
DOI 10.1111/sjos.12451
Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
Mol Psychiatry, 26 (9), 5124-5139
DOI 10.1038/s41380-020-0754-0, PubMed 32424236
In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 385-398
DOI 10.1002/hbm.25249, PubMed 33073925
Disentangling the relationship between cholesterol, aggression, and impulsivity in severe mental disorders
Brain Behav, 10 (9), e01751
DOI 10.1002/brb3.1751, PubMed 32681586
Childhood trauma is associated with poorer social functioning in severe mental disorders both during an active illness phase and in remission
Schizophr Res, 243, 241-246
DOI 10.1016/j.schres.2020.03.015, PubMed 32222348
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
Nat Commun, 11 (1), 4796
DOI 10.1038/s41467-020-18367-y, PubMed 32963231
Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model
PLoS Genet, 16 (5), e1008612
DOI 10.1371/journal.pgen.1008612, PubMed 32427991
The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium
Am J Psychiatry, 177 (6), 537-547
DOI 10.1176/appi.ajp.2019.19030225, PubMed 32212855
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia: A comparison among participants between 2 and 53 years
FASEB J, 34 (6), 8114-8124
DOI 10.1096/fj.201900855RRR, PubMed 32323402
A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data
Cancer Epidemiol Biomarkers Prev, 29 (9), 1731-1738
DOI 10.1158/1055-9965.EPI-19-1527, PubMed 32581112
Age dependence of modern clinical risk groups for localized prostate cancer-A population-based study
Cancer, 126 (8), 1691-1699
DOI 10.1002/cncr.32702, PubMed 31899813
Differences in the Presentation and Progression of Parkinson's Disease by Sex
Mov Disord, 36 (1), 106-117
DOI 10.1002/mds.28312, PubMed 33002231
Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 52 (3), 354
DOI 10.1038/s41588-019-0573-x, PubMed 32029921
The effect of sample size on polygenic hazard models for prostate cancer
Eur J Hum Genet, 28 (10), 1467-1475
DOI 10.1038/s41431-020-0664-2, PubMed 32514134
African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer
Int J Cancer, 148 (1), 99-105
DOI 10.1002/ijc.33282, PubMed 32930425
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research
Hum Brain Mapp, 43 (1), 194-206
DOI 10.1002/hbm.24998, PubMed 32301246
Cortical thickness and resting-state cardiac function across the lifespan: A cross-sectional pooled mega-analysis
Psychophysiology, 58 (7), e13688
DOI 10.1111/psyp.13688, PubMed 33037836
Undetectable or subtherapeutic serum levels of antipsychotic drugs preceding switch to clozapine
NPJ Schizophr, 6 (1), 17
DOI 10.1038/s41537-020-0107-7, PubMed 32681055
Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: results from the ENIGMA MDD Working Group
Transl Psychiatry, 10 (1), 425
DOI 10.1038/s41398-020-01109-5, PubMed 33293520
Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population
PLoS One, 15 (4), e0232292
DOI 10.1371/journal.pone.0232292, PubMed 32343744
Differences in directed functional brain connectivity related to age, sex and mental health
Hum Brain Mapp, 41 (15), 4173-4186
DOI 10.1002/hbm.25116, PubMed 32613721
Associations between schizophrenia polygenic risk and apathy in schizophrenia spectrum disorders and healthy controls
Acta Psychiatr Scand, 141 (5), 452-464
DOI 10.1111/acps.13167, PubMed 32091622
Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action
Eur Neuropsychopharmacol, 36, 121-136
DOI 10.1016/j.euroneuro.2020.05.006, PubMed 32536571
Interleukin 18 (IL-18) and its binding protein (IL-18BP) are increased in patients with epilepsy suggesting low-grade systemic inflammation
Seizure, 80, 221-225
DOI 10.1016/j.seizure.2020.05.018, PubMed 32659652
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
Addict Biol, 26 (1), e12880
DOI 10.1111/adb.12880, PubMed 32064741
The role of norepinephrine in the pathophysiology of schizophrenia
Neurosci Biobehav Rev, 118, 298-314
DOI 10.1016/j.neubiorev.2020.07.038, PubMed 32768486
Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study
Hum Brain Mapp, 41 (16), 4676-4690
DOI 10.1002/hbm.25149, PubMed 32744409
Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents
Transl Psychiatry, 10 (1), 251
DOI 10.1038/s41398-020-00931-1, PubMed 32710012
Age of First Walking and Associations with Symptom Severity in Children with Suspected or Diagnosed Autism Spectrum Disorder
J Autism Dev Disord, 50 (9), 3216-3232
DOI 10.1007/s10803-019-04112-y, PubMed 31278523
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
Schizophr Bull, 46 (2), 336-344
DOI 10.1093/schbul/sbz061, PubMed 31206164
Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders
Hum Brain Mapp, 42 (6), 1714-1726
DOI 10.1002/hbm.25323, PubMed 33340180
Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap
Mol Psychiatry, 26 (3), 722-724
DOI 10.1038/s41380-020-00915-z, PubMed 33060817
Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR
Bioinformatics, 36 (18), 4749-4756
DOI 10.1093/bioinformatics/btaa568, PubMed 32539089
Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease
Mov Disord, 36 (2), 449-459
DOI 10.1002/mds.28338, PubMed 33107653
Nonsocial cognitive underpinnings of theory of mind in schizophrenia
Psychiatry Res, 289, 113055
DOI 10.1016/j.psychres.2020.113055, PubMed 32446008
Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 914
DOI 10.1038/s41380-019-0456-7, PubMed 31308466
The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology
Nat Rev Neurol, 16 (7), 366-379
DOI 10.1038/s41582-020-0364-0, PubMed 32528109
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
Biol Psychiatry, 89 (3), 227-235
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043
Negative and disorganized symptoms mediate the relationship between verbal learning and global functioning in adolescents with early-onset psychosis
Eur Child Adolesc Psychiatry, 29 (12), 1693-1703
DOI 10.1007/s00787-020-01479-7, PubMed 32036438
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 198
DOI 10.1038/s41398-020-00888-1, PubMed 32555152
Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 366
DOI 10.1038/s41398-020-01061-4, PubMed 33139722
Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs - A study based on blood sample analyses from 24,239 patients
Eur Neuropsychopharmacol, 37, 64-69
DOI 10.1016/j.euroneuro.2020.06.007, PubMed 32595082
Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders
Schizophr Res, 228, 590-596
DOI 10.1016/j.schres.2020.11.025, PubMed 33221147
Childhood Trauma in Persons With Schizophrenia and a History of Interpersonal Violence
Front Psychiatry, 11, 383
DOI 10.3389/fpsyt.2020.00383, PubMed 32431632
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224
Exploring neurophysiological markers of visual perspective taking: Methodological considerations
Int J Psychophysiol, 161, 1-12
DOI 10.1016/j.ijpsycho.2020.12.006, PubMed 33388368
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Mol Psychiatry, 25 (3), 692-695
DOI 10.1038/s41380-019-0358-8, PubMed 30705424
Insulin Resistance and Oxidative Stress: In Relation to Cognitive Function and Psychopathology in Drug-Naïve, First-Episode Drug-Free Schizophrenia
Front Psychiatry, 11, 537280
DOI 10.3389/fpsyt.2020.537280, PubMed 33329081
Hippocampal subfield and amygdala nuclei volumes in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 270 (6), 771-782
DOI 10.1007/s00406-020-01098-y, PubMed 31980898
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Transl Psychiatry, 10 (1), 100
DOI 10.1038/s41398-020-0705-1, PubMed 32198361
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 5 (12), 1095-1103
DOI 10.1016/j.bpsc.2020.06.014, PubMed 32859549
Experience-dependent modulation of the visual evoked potential: Testing effect sizes, retention over time, and associations with age in 415 healthy individuals
Neuroimage, 223, 117302
DOI 10.1016/j.neuroimage.2020.117302, PubMed 32828930
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area
Cereb Cortex, 30 (10), 5597-5603
DOI 10.1093/cercor/bhaa146, PubMed 32483632
Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 3512
DOI 10.1038/s41467-020-17368-1, PubMed 32665545
Author Correction: Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 4700
DOI 10.1038/s41467-020-18628-w, PubMed 32929091
Cognitive Heterogeneity across Schizophrenia and Bipolar Disorder: A Cluster Analysis of Intellectual Trajectories
J Int Neuropsychol Soc, 26 (9), 860-872
DOI 10.1017/S1355617720000442, PubMed 32423506
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
PLoS Genet, 16 (11), e1009163
DOI 10.1371/journal.pgen.1009163, PubMed 33227023
Author Correction: A global overview of pleiotropy and genetic architecture in complex traits
Nat Genet, 52 (3), 353
DOI 10.1038/s41588-019-0571-z, PubMed 32029922
Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
NPJ Schizophr, 6 (1), 20
DOI 10.1038/s41537-020-00112-5, PubMed 32811840
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
Schizophr Res, 218, 55-62
DOI 10.1016/j.schres.2020.03.006, PubMed 32171635
Greater male than female variability in regional brain structure across the lifespan
Hum Brain Mapp, 43 (1), 470-499
DOI 10.1002/hbm.25204, PubMed 33044802
Associations of loneliness and social isolation with cardiovascular and metabolic health: a systematic review and meta-analysis protocol
Syst Rev, 9 (1), 102
DOI 10.1186/s13643-020-01369-8, PubMed 32366295
Improving the precision of intranasal oxytocin research
Nat Hum Behav, 5 (1), 9-18
DOI 10.1038/s41562-020-00996-4, PubMed 33257880
Asphyxia at birth affects brain structure in patients on the schizophrenia-bipolar disorder spectrum and healthy participants
Psychol Med, 52 (6), 1050-1059
DOI 10.1017/S0033291720002779, PubMed 32772969
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
JAMA Psychiatry, 77 (4), 420-430
DOI 10.1001/jamapsychiatry.2019.3779, PubMed 31665216
Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
Front Psychiatry, 11, 391
DOI 10.3389/fpsyt.2020.00391, PubMed 32528319
Publications 2019
Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study
Neuropsychopharmacology, 45 (6), 947-955
DOI 10.1038/s41386-019-0556-8, PubMed 31652432
Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk
JAMA Psychiatry, 76 (7), 739-748
DOI 10.1001/jamapsychiatry.2019.0257, PubMed 30969333
Association between solar insolation and a history of suicide attempts in bipolar I disorder
J Psychiatr Res, 113, 1-9
DOI 10.1016/j.jpsychires.2019.03.001, PubMed 30878786
Shared Genetic Risk of Schizophrenia and Gray Matter Reduction in 6p22.1
Schizophr Bull, 45 (1), 222-232
DOI 10.1093/schbul/sby010, PubMed 29474680
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease
Transl Psychiatry, 9 (1), 273
DOI 10.1038/s41398-019-0592-5, PubMed 31641104
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 10 (1), 2068
DOI 10.1038/s41467-019-10160-w, PubMed 31043617
Population-based neuroimaging reveals traces of childbirth in the maternal brain
Proc Natl Acad Sci U S A, 116 (44), 22341-22346
DOI 10.1073/pnas.1910666116, PubMed 31615888
The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder
Biol Psychiatry, 86 (7), 545-556
DOI 10.1016/j.biopsych.2019.03.985, PubMed 31443932
Antipsychotic treatment and basal ganglia volumes: Exploring the role of receptor occupancy, dosage and remission status
Schizophr Res, 208, 114-123
DOI 10.1016/j.schres.2019.04.002, PubMed 31006616
Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes
Front Neurosci, 13, 220
DOI 10.3389/fnins.2019.00220, PubMed 30930738
Genetic risk for coronary heart disease alters the influence of Alzheimer's genetic risk on mild cognitive impairment
Neurobiol Aging, 84, 237.e5-237.e12
DOI 10.1016/j.neurobiolaging.2019.06.001, PubMed 31272697
Objectively Assessed Daily Steps-Not Light Intensity Physical Activity, Moderate-to-Vigorous Physical Activity and Sedentary Time-Is Associated With Cardiorespiratory Fitness in Patients With Schizophrenia
Front Psychiatry, 10, 82
DOI 10.3389/fpsyt.2019.00082, PubMed 30863327
Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals
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Correction: Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals
Neuropsychopharmacology, 44 (13), 2298
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Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
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Theory of mind in schizophrenia and bipolar disorder: psychometric properties of the Norwegian version of the Hinting Task
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Improvement in verbal learning over the first year of antipsychotic treatment is associated with serum HDL levels in a cohort of first episode psychosis patients
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Association between leptin levels and severity of suicidal behaviour in schizophrenia spectrum disorders
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Identification of common genetic risk variants for autism spectrum disorder
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Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder
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The Association Between Cardiorespiratory Fitness and Cognition Appears Neither Related to Current Physical Activity Nor Mediated by Brain-Derived Neurotrophic Factor in a Sample of Outpatients With Schizophrenia
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Cross-Sectional and Longitudinal MRI Brain Scans Reveal Accelerated Brain Aging in Multiple Sclerosis
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Atypical event-related potentials revealed during the passive parts of a Go-NoGo task in autism spectrum disorder: a case-control study
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Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder
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The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease
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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
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Distinct structural brain circuits indicate mood and apathy profiles in bipolar disorder
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Common brain disorders are associated with heritable patterns of apparent aging of the brain
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Pupillary dilation responses as a midlife indicator of risk for Alzheimer's disease: association with Alzheimer's disease polygenic risk
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways
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Sleep disturbances in schizophrenia spectrum and bipolar disorders - a transdiagnostic perspective
Compr Psychiatry, 91, 6-12
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Brain Connectome Mapping of Complex Human Traits and Their Polygenic Architecture Using Machine Learning
Biol Psychiatry, 87 (8), 717-726
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Cerebellar Gray Matter Volume Is Associated With Cognitive Function and Psychopathology in Adolescence
Biol Psychiatry, 86 (1), 65-75
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GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
Am J Psychiatry, 176 (8), 651-660
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Computational Modeling of Genetic Contributions to Excitability and Neural Coding in Layer V Pyramidal Cells: Applications to Schizophrenia Pathology
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Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
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Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
Cereb Cortex, 29 (2), 875-891
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Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
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Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
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Roadmap for a precision-medicine initiative in the Nordic region
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Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder
Mol Psychiatry, 26 (8), 4055-4065
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Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment
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Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nat Genet, 51 (7), 1193
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Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder A Mendelian Randomization Study
JAMA Netw. Open, 2 (5), e193447
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Oxytocin pathway gene networks in the human brain
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GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
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Sci Rep, 9 (1), 15168
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Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
Acta Psychiatr Scand, 139 (4), 348-360
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GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies
Bioinformatics, 35 (1), 1-11
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Genetic architecture of subcortical brain structures in 38,851 individuals
Nat Genet, 51 (11), 1624-1636
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Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder
Transl Psychiatry, 9 (1), 12
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Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
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Perceived and experienced stigma in first-episode psychosis: A 1-year follow-up study
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Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 844-853
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The emerging pattern of shared polygenic architecture of psychiatric disorders, conceptual and methodological challenges
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Discovery of shared genomic loci using the conditional false discovery rate approach
Hum Genet, 139 (1), 85-94
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Healthy Adolescent Performance With Standardized Scoring Tables for the MATRICS Consensus Cognitive Battery: A Multisite Study
Schizophr Bull, 45 (4), 773-783
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Reduction in N-Desmethylclozapine Level Is Determined by Daily Dose But Not Serum Concentration of Valproic Acid-Indications of a Presystemic Interaction Mechanism
Ther Drug Monit, 41 (4), 503-508
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Correction to: Psychiatric genetics and the structure of psychopathology
Mol Psychiatry, 24 (3), 471
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A five-year follow-up study of antioxidants, oxidative stress and polyunsaturated fatty acids in schizophrenia
Acta Neuropsychiatr, 31 (4), 202-212
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Genome-wide association study identifies 30 loci associated with bipolar disorder
Nat Genet, 51 (5), 793-803
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Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
Psychol Med, 50 (4), 595-606
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A preliminary study of cortical morphology in schizophrenia patients with a history of violence
Psychiatry Res Neuroimaging, 288, 29-36
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Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration
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White matter microstructure in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 271 (4), 623-634
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Autism spectrum disorder polygenic scores are associated with every day executive function in children admitted for clinical assessment
Autism Res, 13 (2), 207-220
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A randomized controlled trial of training of affect recognition (TAR) in schizophrenia shows lasting effects for theory of mind
Eur Arch Psychiatry Clin Neurosci, 269 (5), 611-620
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Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI
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Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations
J Affect Disord, 252, 350-357
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A global overview of pleiotropy and genetic architecture in complex traits
Nat Genet, 51 (9), 1339-1348
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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Nat Genet, 51 (8), 1207-1214
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Lipid alterations in adolescents with early-onset psychosis may be independent of antipsychotic medication
Schizophr Res, 216, 295-301
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Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms
Psychoneuroendocrinology, 112, 104513
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Population-Based Mapping of Polygenic Risk for Schizophrenia on the Human Brain: New Opportunities to Capture the Dimensional Aspects of Severe Mental Disorders
Biol Psychiatry, 86 (7), 499-501
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Obstetric complications and intelligence in patients on the schizophrenia-bipolar spectrum and healthy participants
Psychol Med, 50 (11), 1914-1922
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Mood episodes are associated with increased cortical thinning: A longitudinal study of bipolar disorder type II
Bipolar Disord, 21 (6), 525-538
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Childhood maltreatment and polygenic risk in bipolar disorders
Bipolar Disord, 22 (2), 174-181
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The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders
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Telomere length is associated with childhood trauma in patients with severe mental disorders
Transl Psychiatry, 9 (1), 97
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Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders
Schizophr Res, 213, 65-71
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Publications 2018
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance
Sci Rep, 8 (1), 12654
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Association of Heritable Cognitive Ability and Psychopathology With White Matter Properties in Children and Adolescents
JAMA Psychiatry, 75 (3), 287-295
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Recently evolved human-specific methylated regions are enriched in schizophrenia signals
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Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia
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Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives
Lancet Psychiatry, 5 (11), 930-939
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Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
PLoS One, 13 (8), e0200250
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Cross-tissue eQTL enrichment of associations in schizophrenia
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CXCR4 involvement in neurodegenerative diseases
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Analysis of shared heritability in common disorders of the brain
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Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
PLoS Med, 15 (1), e1002487
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Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
PLoS Med, 15 (1), e1002504
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Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease
Acta Neuropathol, 137 (2), 209-226
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Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 9 (1), 2098
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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
Nat Genet, 51 (1), 63-75
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An association between YKL-40 and type 2 diabetes in psychotic disorders
Acta Psychiatr Scand, 139 (1), 37-45
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Clinical characteristics of patients with bipolar disorder and premorbid traumatic brain injury: a cross-sectional study
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Reliability and validity of the self-report version of the apathy evaluation scale in first-episode Psychosis: Concordance with the clinical version at baseline and 12 months follow-up
Psychiatry Res, 267, 140-147
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Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes
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Beyond heritability: improving discoverability in imaging genetics
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Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders
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Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker
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Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders
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Hippocampus volume reduction in psychosis spectrum could be ameliorated by vitamin D
Schizophr Res, 199, 433-435
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Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls
Sci Rep, 8 (1), 10817
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Cardio-respiratory fitness is associated with a verbal factor across cognitive domains in schizophrenia
Schizophr Res, 206, 157-162
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Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
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Attenuated Notch signaling in schizophrenia and bipolar disorder
Sci Rep, 8 (1), 5349
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Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Transl Psychiatry, 8 (1), 210
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Widespread white matter changes in post-H1N1 patients with narcolepsy type 1 and first-degree relatives
Sleep, 41 (10)
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Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum
JAMA Neurol, 75 (7), 860-875
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Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia
JAMA Psychiatry, 75 (7), 749-751
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Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease
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Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia
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Key Brain Network Nodes Show Differential Cognitive Relevance and Developmental Trajectories during Childhood and Adolescence
eNeuro, 5 (4)
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In Vivo Two-Photon Voltage Imaging with Sulfonated Rhodamine Dyes
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Psychedelic drugs in the treatment of anxiety, depression and addiction
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Psychedelic drugs in the treatment of anxiety, depression and addiction
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Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
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A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
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A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia
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Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex
Sci Rep, 8 (1), 13373
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Use of an Alzheimer's disease polygenic risk score to identify mild cognitive impairment in adults in their 50s
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Cortical thickness abnormalities in bipolar disorder patients with a lifetime history of auditory hallucinations
Bipolar Disord, 20 (7), 647-657
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Probing Brain Developmental Patterns of Myelination and Associations With Psychopathology in Youths Using Gray/White Matter Contrast
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Using structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Mol Psychiatry, 25 (9), 2130-2143
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nat Genet, 50 (3), 381-389
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Evidence for intranasal oxytocin delivery to the brain: recent advances and future perspectives
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The Promise of Intranasal Esketamine as a Novel and Effective Antidepressant
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Low-dose intranasal oxytocin delivered with Breath Powered device modulates pupil diameter and amygdala activity: a randomized controlled pupillometry and fMRI study
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Saliva oxytocin measures do not reflect peripheral plasma concentrations after intranasal oxytocin administration in men
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Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry
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Cardiometabolic risk factors, physical activity and psychiatric status in patients in long-term psychiatric inpatient departments
Nord J Psychiatry, 72 (4), 296-302
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Using motivational techniques to reduce cardiometabolic risk factors in long term psychiatric inpatients: a naturalistic interventional study
BMC Psychiatry, 18 (1), 255
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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Nat Genet, 50 (7), 912-919
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Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts
BMJ, 360, j5757
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Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder
Brain Imaging Behav, 12 (3), 640-652
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How can genetics help understand the relationship between cognitive dysfunction and schizophrenia?
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Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms
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Psychiatric genetics and the structure of psychopathology
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Restriction spectrum imaging of white matter and its relation to neurological disability in multiple sclerosis
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Enrichment of genetic markers of recent human evolution in educational and cognitive traits
Sci Rep, 8 (1), 12585
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Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
Sci Rep, 8 (1), 6915
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Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
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Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays
Nat Commun, 9 (1), 2035
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Metacognitive Aspects of Executive Function Are Highly Associated with Social Functioning on Parent-Rated Measures in Children with Autism Spectrum Disorder
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White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging
Sci Rep, 8 (1), 14129
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Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
Mol Psychiatry, 25 (11), 3053-3065
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Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
Biol Psychiatry, 84 (9), 644-654
DOI 10.1016/j.biopsych.2018.04.023, PubMed 29960671
Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?
Biol Psychiatry, 85 (7), e35-e39
DOI 10.1016/j.biopsych.2018.10.003, PubMed 30470561
Emotion perception, non-social cognition and symptoms as predictors of theory of mind in schizophrenia
Compr Psychiatry, 85, 1-7
DOI 10.1016/j.comppsych.2018.05.002, PubMed 29906670
Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication
J Psychiatr Res, 106, 74-81
DOI 10.1016/j.jpsychires.2018.09.014, PubMed 30292780
Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?
J Psychiatr Res, 117, 150
DOI 10.1016/j.jpsychires.2018.11.012, PubMed 30454945
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume
Nat Commun, 9 (1), 3945
DOI 10.1038/s41467-018-06234-w, PubMed 30258056
Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci
Sci Rep, 8 (1), 18088
DOI 10.1038/s41598-018-36429-6, PubMed 30591712
Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models
JAMA Psychiatry, 75 (11), 1146-1155
DOI 10.1001/jamapsychiatry.2018.2467, PubMed 30304337
Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals
Transl Psychiatry, 8 (1), 103
DOI 10.1038/s41398-018-0151-5, PubMed 29795193
Identification of shared genetic variants between schizophrenia and lung cancer
Sci Rep, 8 (1), 674
DOI 10.1038/s41598-017-16481-4, PubMed 29330379
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813
Publications 2017
Diabetes and Schizophrenia-New Findings for an Old Puzzle
Am J Psychiatry, 174 (7), 616-617
DOI 10.1176/appi.ajp.2017.17040409, PubMed 28669214
eHealth provides a novel opportunity to exploit the advantages of the Nordic countries in psychiatric genetic research, building on the public health care system, biobanks, and registries
Am J Med Genet B Neuropsychiatr Genet, 177 (7), 625-629
DOI 10.1002/ajmg.b.32561, PubMed 28686333
Solar insolation in springtime influences age of onset of bipolar I disorder
Acta Psychiatr Scand, 136 (6), 571-582
DOI 10.1111/acps.12772, PubMed 28722128
Right unilateral electroconvulsive therapy does not cause more cognitive impairment than pharmacologic treatment in treatment-resistant bipolar depression: A 6-month randomized controlled trial follow-up study
Bipolar Disord, 20 (6), 531-538
DOI 10.1111/bdi.12594, PubMed 29267990
Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure
Sci Rep, 7 (1), 15736
DOI 10.1038/s41598-017-15705-x, PubMed 29147026
Genetic factors influencing prostate cancer risk in Norwegian men
Prostate, 78 (3), 186-192
DOI 10.1002/pros.23453, PubMed 29181843
Childhood Trauma and Minimization/Denial in People with and without a Severe Mental Disorder
Front Psychol, 8, 1276
DOI 10.3389/fpsyg.2017.01276, PubMed 28883800
Disrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer's disease continuum
Sci Rep, 7, 40268
DOI 10.1038/srep40268, PubMed 28074926
Neurocognitive functioning, clinical course and functional outcome in first-treatment bipolar I disorder patients with and without clinical relapse: A 1-year follow-up study
Bipolar Disord, 20 (3), 228-237
DOI 10.1111/bdi.12569, PubMed 29121444
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score
PLoS Med, 14 (3), e1002258
DOI 10.1371/journal.pmed.1002258, PubMed 28323831
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
Mol Psychiatry, 22 (6), 792-801
DOI 10.1038/mp.2017.33, PubMed 28348379
Dissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer's disease spectrum
Sci Rep, 7, 45131
DOI 10.1038/srep45131, PubMed 28338052
Distinguishing early and late brain aging from the Alzheimer's disease spectrum: consistent morphological patterns across independent samples
Neuroimage, 158, 282-295
DOI 10.1016/j.neuroimage.2017.06.070, PubMed 28666881
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
Neuroimage Clin, 15, 719-731
DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349
Increased sensitivity to age-related differences in brain functional connectivity during continuous multiple object tracking compared to resting-state
Neuroimage, 148, 364-372
DOI 10.1016/j.neuroimage.2017.01.048, PubMed 28111190
Body language reading of emotion in schizophrenia: Associations with symptoms and functional outcome
Scand J Psychol, 58 (5), 359-366
DOI 10.1111/sjop.12381, PubMed 28833180
Metabolic risk factors in schizophrenia and bipolar disorder: The effect of comedication with selective serotonin reuptake inhibitors and antipsychotics
Eur Psychiatry, 48, 71-78
DOI 10.1016/j.eurpsy.2017.04.001, PubMed 29331603
Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis
Schizophr Res, 197, 253-260
DOI 10.1016/j.schres.2017.10.042, PubMed 29129510
4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients
Br J Clin Pharmacol, 83 (11), 2398-2405
DOI 10.1111/bcp.13341, PubMed 28585378
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
Brain Imaging Behav, 11 (5), 1497-1514
DOI 10.1007/s11682-016-9629-z, PubMed 27738994
Biclustered Independent Component Analysis for Complex Biomarker and Subtype Identification from Structural Magnetic Resonance Images in Schizophrenia
Front Psychiatry, 8, 179
DOI 10.3389/fpsyt.2017.00179, PubMed 29018368
Ion diffusion may introduce spurious current sources in current-source density (CSD) analysis
J Neurophysiol, 118 (1), 114-120
DOI 10.1152/jn.00976.2016, PubMed 28298307
Cortical thickness, cortical surface area and subcortical volumes in schizophrenia and bipolar disorder patients with cannabis use
Eur Neuropsychopharmacol, 28 (1), 37-47
DOI 10.1016/j.euroneuro.2017.11.019, PubMed 29254657
Predicting Outcome 12 Months after Mild Traumatic Brain Injury in Patients Admitted to a Neurosurgery Service
Front Neurol, 8, 125
DOI 10.3389/fneur.2017.00125, PubMed 28443058
White matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury
Sci Rep, 7 (1), 13795
DOI 10.1038/s41598-017-13628-1, PubMed 29061970
Longitudinal changes in brain morphology from 4 weeks to 12 months after mild traumatic brain injury: Associations with cognitive functions and clinical variables
Brain Inj, 31 (5), 674-685
DOI 10.1080/02699052.2017.1283537, PubMed 28414250
Novel genetic loci associated with hippocampal volume
Nat Commun, 8, 13624
DOI 10.1038/ncomms13624, PubMed 28098162
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group
Mol Psychiatry, 23 (4), 932-942
DOI 10.1038/mp.2017.73, PubMed 28461699
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760
The relation between face-emotion recognition and social function in adolescents with autism spectrum disorders: A case control study
PLoS One, 12 (10), e0186124
DOI 10.1371/journal.pone.0186124, PubMed 29020059
Event-Related Potentials in a Cued Go-NoGo Task Associated with Executive Functions in Adolescents with Autism Spectrum Disorder; A Case-Control Study
Front Neurosci, 11, 393
DOI 10.3389/fnins.2017.00393, PubMed 28744191
Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy
Prog Neuropsychopharmacol Biol Psychiatry, 82, 263-271
DOI 10.1016/j.pnpbp.2017.11.004, PubMed 29122637
Parents' Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder-Data from a Norwegian Sample
Int J Mol Sci, 18 (5)
DOI 10.3390/ijms18051078, PubMed 28524073
Delayed stabilization and individualization in connectome development are related to psychiatric disorders
Nat Neurosci, 20 (4), 513-515
DOI 10.1038/nn.4511, PubMed 28218917
Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
Mol Psychiatry, 23 (5), 1261-1269
DOI 10.1038/mp.2017.170, PubMed 29038599
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
Cell Rep, 21 (9), 2597-2613
DOI 10.1016/j.celrep.2017.11.028, PubMed 29186694
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
Schizophr Bull, 43 (3), 654-664
DOI 10.1093/schbul/sbw085, PubMed 27338279
Modeling prior information of common genetic variants improves gene discovery for neuroticism
Hum Mol Genet, 26 (22), 4530-4539
DOI 10.1093/hmg/ddx340, PubMed 28973307
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Psychol Med, 48 (7), 1201-1208
DOI 10.1017/S0033291717002665, PubMed 28942743
Combinations of genetic variants associated with bipolar disorder
PLoS One, 12 (12), e0189739
DOI 10.1371/journal.pone.0189739, PubMed 29267373
Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls
Mol Psychiatry, 23 (6), 1512-1520
DOI 10.1038/mp.2017.106, PubMed 28507318
A stepwise neuron model fitting procedure designed for recordings with high spatial resolution: Application to layer 5 pyramidal cells
J Neurosci Methods, 293, 264-283
DOI 10.1016/j.jneumeth.2017.10.007, PubMed 28993204
Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling
Transl Psychiatry, 7 (11), 5
DOI 10.1038/s41398-017-0007-4, PubMed 30446648
Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study
Acta Psychiatr Scand, 136 (4), 400-408
DOI 10.1111/acps.12783, PubMed 28815548
Vitamin D Deficiency Associated With Cognitive Functioning in Psychotic Disorders
J Clin Psychiatry, 78 (7), e750-e757
DOI 10.4088/JCP.16m10880, PubMed 28493652
The quality of severe mental disorder diagnoses in a national health registry as compared to research diagnoses based on structured interview
BMC Psychiatry, 17 (1), 93
DOI 10.1186/s12888-017-1256-8, PubMed 28292279
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
NPJ Genom Med, 2, 24
DOI 10.1038/s41525-017-0027-2, PubMed 29263835
Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data
Transl Psychiatry, 7 (12), 1289
DOI 10.1038/s41398-017-0033-2, PubMed 29249828
Oxytocin system dysfunction as a common mechanism underlying metabolic syndrome and psychiatric symptoms in schizophrenia and bipolar disorders
Front Neuroendocrinol, 45, 1-10
DOI 10.1016/j.yfrne.2016.12.004, PubMed 28049009
Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults
PLoS One, 12 (2), e0170921
DOI 10.1371/journal.pone.0170921, PubMed 28151944
Dose-dependent social-cognitive effects of intranasal oxytocin delivered with novel Breath Powered device in adults with autism spectrum disorder: a randomized placebo-controlled double-blind crossover trial
Transl Psychiatry, 7 (5), e1136
DOI 10.1038/tp.2017.103, PubMed 28534875
[Medication-free hospital records - a measure not based on knowledge]
Tidsskr Nor Laegeforen, 137 (6), 426-427
DOI 10.4045/tidsskr.17.0091, PubMed 28332789
[Not Available]
Tidsskr Nor Laegeforen, 137 (9), 594-595
DOI 10.4045/tidsskr.17.0288, PubMed 28468447
Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment
J Am Acad Child Adolesc Psychiatry, 57 (2), 86-95
DOI 10.1016/j.jaac.2017.11.013, PubMed 29413154
Consistent Functional Connectivity Alterations in Schizophrenia Spectrum Disorder: A Multisite Study
Schizophr Bull, 43 (4), 914-924
DOI 10.1093/schbul/sbw145, PubMed 27872268
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
JAMA Psychiatry, 74 (10), 1065-1075
DOI 10.1001/jamapsychiatry.2017.1986, PubMed 28746715
Identification of genetic loci shared between schizophrenia and the Big Five personality traits
Sci Rep, 7 (1), 2222
DOI 10.1038/s41598-017-02346-3, PubMed 28533504
Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study
CNS Drugs, 31 (11), 991-997
DOI 10.1007/s40263-017-0469-1, PubMed 28948574
Probing the Association between Early Evolutionary Markers and Schizophrenia
PLoS One, 12 (1), e0169227
DOI 10.1371/journal.pone.0169227, PubMed 28081145
Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis
Nat Genet, 49 (5), 801-805
DOI 10.1038/ng.3816, PubMed 28319091
Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis
Nat Genet, 49 (8), 1286
DOI 10.1038/ng0817-1286b, PubMed 28747754
Psychiatric Genomics: An Update and an Agenda
Am J Psychiatry, 175 (1), 15-27
DOI 10.1176/appi.ajp.2017.17030283, PubMed 28969442
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition
Acta Neuropathol, 135 (1), 85-93
DOI 10.1007/s00401-017-1789-4, PubMed 29177679
Polygenic hazard scores in preclinical Alzheimer disease
Ann Neurol, 82 (3), 484-488
DOI 10.1002/ana.25029, PubMed 28940650
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (3), 336-345
DOI 10.1038/mp.2016.244, PubMed 28093568
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (11), 1651-1652
DOI 10.1038/mp.2017.197, PubMed 29068436
The correlation between central and peripheral oxytocin concentrations: A systematic review and meta-analysis
Neurosci Biobehav Rev, 78, 117-124
DOI 10.1016/j.neubiorev.2017.04.017, PubMed 28442403
Impairment in emotion perception from body movements in individuals with bipolar I and bipolar II disorder is associated with functional capacity
Int J Bipolar Disord, 5 (1), 13
DOI 10.1186/s40345-017-0083-7, PubMed 28332121
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium
Acta Psychiatr Scand, 135 (5), 439-447
DOI 10.1111/acps.12718, PubMed 28369804
Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium
Psychol Med, 48 (1), 82-94
DOI 10.1017/S0033291717001283, PubMed 28545597
Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants
PLoS One, 12 (9), e0185663
DOI 10.1371/journal.pone.0185663, PubMed 28957430
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
JAMA Neurol, 74 (7), 780-792
DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Transl Psychiatry, 7 (6), e1155
DOI 10.1038/tp.2017.115, PubMed 28632202
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia
Acta Neuropathol, 133 (5), 825-837
DOI 10.1007/s00401-017-1693-y, PubMed 28271184
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
BMC Genomics, 18 (1), 270
DOI 10.1186/s12864-017-3620-y, PubMed 28359301
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247
Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not
Psychol Med, 48 (1), 43-49
DOI 10.1017/S0033291717001209, PubMed 28967348
Publications 2016
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Nat Neurosci, 19 (12), 1569-1582
DOI 10.1038/nn.4398, PubMed 27694991
A genetic association study of CSMD1 and CSMD2 with cognitive function
Brain Behav Immun, 61, 209-216
DOI 10.1016/j.bbi.2016.11.026, PubMed 27890662
Modelling difficulties in abstract thinking in psychosis: the importance of socio-developmental background
Cogn Neuropsychiatry, 22 (1), 39-52
DOI 10.1080/13546805.2016.1259998, PubMed 28005457
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease
Ann Clin Transl Neurol, 3 (9), 668-77
DOI 10.1002/acn3.333, PubMed 27648456
Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels
Acta Psychiatr Scand, 134 (1), 40-7
DOI 10.1111/acps.12576, PubMed 27028967
History of psychosis and previous episodes as potential explanatory factors for neurocognitive impairment in first-treatment bipolar I disorder
Bipolar Disord, 18 (2), 136-47
DOI 10.1111/bdi.12377, PubMed 26990158
Course of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study
Psychiatry Res, 249, 286-292
DOI 10.1016/j.psychres.2016.12.048, PubMed 28142102
Somatic Comorbidity in Schizophrenia: Some Possible Biological Mechanisms Across the Life Span
Schizophr Bull, 42 (6), 1316-1319
DOI 10.1093/schbul/sbw028, PubMed 27033328
Age-related differences in brain network activation and co-activation during multiple object tracking
Brain Behav, 6 (11), e00533
DOI 10.1002/brb3.533, PubMed 27843692
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Nat Genet, 48 (5), 510-8
DOI 10.1038/ng.3528, PubMed 26974007
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
J Neurol Neurosurg Psychiatry, 88 (2), 152-164
DOI 10.1136/jnnp-2016-314411, PubMed 27899424
Metabolic Abnormalities Related to Treatment With Selective Serotonin Reuptake Inhibitors in Patients With Schizophrenia or Bipolar Disorder
J Clin Psychopharmacol, 36 (6), 615-620
DOI 10.1097/JCP.0000000000000582, PubMed 27749681
Relationship of suicide rates with climate and economic variables in Europe during 2000-2012
Ann Gen Psychiatry, 15, 19
DOI 10.1186/s12991-016-0106-2, PubMed 27508001
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
Nat Neurosci, 19 (3), 420-431
DOI 10.1038/nn.4228, PubMed 26854805
Random Projection for Fast and Efficient Multivariate Correlation Analysis of High-Dimensional Data: A New Approach
Front Genet, 7, 102
DOI 10.3389/fgene.2016.00102, PubMed 27375677
A sequence variant associating with educational attainment also affects childhood cognition
Sci Rep, 6, 36189
DOI 10.1038/srep36189, PubMed 27811963
Effect of Ionic Diffusion on Extracellular Potentials in Neural Tissue
PLoS Comput Biol, 12 (11), e1005193
DOI 10.1371/journal.pcbi.1005193, PubMed 27820827
Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders
BJPsych Open, 2 (6), 353-358
DOI 10.1192/bjpo.bp.116.003376, PubMed 27847593
The Association between Anomalous Self-experiences, Self-esteem and Depressive Symptoms in First Episode Schizophrenia
Front Hum Neurosci, 10, 557
DOI 10.3389/fnhum.2016.00557, PubMed 27872587
Volumetric and morphometric MRI findings in patients with mild traumatic brain injury
Brain Inj, 30 (13-14), 1683-1691
DOI 10.1080/02699052.2016.1199905, PubMed 27996331
Subcortical volumetric abnormalities in bipolar disorder
Mol Psychiatry, 21 (12), 1710-1716
DOI 10.1038/mp.2015.227, PubMed 26857596
Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics
Front Genet, 7, 15
DOI 10.3389/fgene.2016.00015, PubMed 26909100
Reduced load-dependent default mode network deactivation across executive tasks in schizophrenia spectrum disorders
Neuroimage Clin, 12, 389-96
DOI 10.1016/j.nicl.2016.08.012, PubMed 27622135
Parents' attitudes toward genetic research in autism spectrum disorder
Psychiatr Genet, 26 (2), 74-80
DOI 10.1097/YPG.0000000000000121, PubMed 26867185
Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder
Psychol Med, 46 (9), 1971-85
DOI 10.1017/S0033291716000593, PubMed 27049014
Brain volume change in first-episode psychosis: an effect of antipsychotic medication independent of BMI change
Acta Psychiatr Scand, 135 (2), 117-126
DOI 10.1111/acps.12677, PubMed 27925164
Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets
Neuroimage, 147, 243-252
DOI 10.1016/j.neuroimage.2016.11.073, PubMed 27916665
Duration of untreated illness in first-treatment bipolar I disorder in relation to clinical outcome and cannabis use
Psychiatry Res, 246, 762-768
DOI 10.1016/j.psychres.2016.07.064, PubMed 27814886
Alcohol use disorders are associated with increased affective lability in bipolar disorder
J Affect Disord, 208, 316-324
DOI 10.1016/j.jad.2016.09.062, PubMed 27810713
Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls
Psychol Med, 47 (4), 655-668
DOI 10.1017/S0033291716002920, PubMed 27830632
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders
Nat Genet, 49 (1), 152-156
DOI 10.1038/ng.3736, PubMed 27918536
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Nat Genet, 49 (1), 27-35
DOI 10.1038/ng.3725, PubMed 27869829
Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women
JAMA Psychiatry, 73 (5), 497-505
DOI 10.1001/jamapsychiatry.2016.0129, PubMed 27007234
Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 1 (1), 49-59
DOI 10.1016/j.bpsc.2015.09.002, PubMed 26949748
Auditory Cortex Characteristics in Schizophrenia: Associations With Auditory Hallucinations
Schizophr Bull, 43 (1), 75-83
DOI 10.1093/schbul/sbw130, PubMed 27605526
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849
Low vitamin D is associated with negative and depressive symptoms in psychotic disorders
Schizophr Res, 178 (1-3), 44-49
DOI 10.1016/j.schres.2016.08.024, PubMed 27595553
The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample
BMC Psychiatry, 16, 129
DOI 10.1186/s12888-016-0732-x, PubMed 27150464
Increased plasma levels of competing amino acids, rather than lowered plasma tryptophan levels, are associated with a non-response to treatment in major depression
Eur Neuropsychopharmacol, 26 (8), 1286-96
DOI 10.1016/j.euroneuro.2016.05.005, PubMed 27237997
Conservation of Distinct Genetically-Mediated Human Cortical Pattern
PLoS Genet, 12 (7), e1006143
DOI 10.1371/journal.pgen.1006143, PubMed 27459196
Resting-state high-frequency heart rate variability is related to respiratory frequency in individuals with severe mental illness but not healthy controls
Sci Rep, 6, 37212
DOI 10.1038/srep37212, PubMed 27853244
The impact of oxytocin administration on brain activity: a systematic review and meta-analysis protocol
Syst Rev, 5 (1), 205
DOI 10.1186/s13643-016-0386-2, PubMed 27899138
Low dose intranasal oxytocin delivered with Breath Powered device dampens amygdala response to emotional stimuli: A peripheral effect-controlled within-subjects randomized dose-response fMRI trial
Psychoneuroendocrinology, 69, 180-8
DOI 10.1016/j.psyneuen.2016.04.010, PubMed 27107209
Reliability of basal plasma vasopressin concentrations in healthy male adults
Acta Neuropsychiatr, 29 (5), 315-321
DOI 10.1017/neu.2016.67, PubMed 27923411
Premorbid cannabis use is associated with more symptoms and poorer functioning in schizophrenia spectrum disorder
Psychol Med, 46 (15), 3127-3136
DOI 10.1017/S0033291716001999, PubMed 27534999
25th Annual Computational Neuroscience Meeting: CNS-2016
BMC Neurosci, 17 Suppl 1 (Suppl 1), 54
DOI 10.1186/s12868-016-0283-6, PubMed 27534393
Global brain connectivity alterations in patients with schizophrenia and bipolar spectrum disorders
J Psychiatry Neurosci, 41 (5), 331-41
DOI 10.1503/jpn.150159, PubMed 26854755
Lipid profiles in schizophrenia associated with clinical traits: a five year follow-up study
BMC Psychiatry, 16 (1), 299
DOI 10.1186/s12888-016-1006-3, PubMed 27562545
Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders
World J Biol Psychiatry, 18 (6), 471-482
DOI 10.1080/15622975.2016.1245441, PubMed 27712130
Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting
Int J Bipolar Disord, 4 (1), 24
DOI 10.1186/s40345-016-0067-z, PubMed 27858347
Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment
Eur Neuropsychopharmacol, 27 (6), 589-598
DOI 10.1016/j.euroneuro.2016.07.011, PubMed 27492885
VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls
Br J Psychiatry, 209 (2), 114-20
DOI 10.1192/bjp.bp.115.161950, PubMed 26941264
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements
Philos Trans R Soc Lond B Biol Sci, 371 (1705)
DOI 10.1098/rstb.2015.0356, PubMed 27574309
Cell type specificity of neurovascular coupling in cerebral cortex
Elife, 5
DOI 10.7554/eLife.14315, PubMed 27244241
The relationship between central and peripheral oxytocin concentrations: a systematic review and meta-analysis protocol
Syst Rev, 5, 49
DOI 10.1186/s13643-016-0225-5, PubMed 27037015
Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis
Biol Psychiatry, 82 (9), 634-641
DOI 10.1016/j.biopsych.2016.08.040, PubMed 27890468
Association of Butyrylcholinesterase-K Allele and Apolipoprotein E ɛ4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease
J Alzheimers Dis, 50 (2), 567-76
DOI 10.3233/JAD-150750, PubMed 26757188
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors
Mult Scler, 22 (14), 1783-1793
DOI 10.1177/1352458516635873, PubMed 26920376
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS
PLoS Genet, 12 (1), e1005803
DOI 10.1371/journal.pgen.1005803, PubMed 26808560
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
JAMA Neurol, 73 (6), 691-7
DOI 10.1001/jamaneurol.2016.0150, PubMed 27088644
Pleiotropic Analysis of Lung Cancer and Blood Triglycerides
J Natl Cancer Inst, 108 (12)
DOI 10.1093/jnci/djw167, PubMed 27565901
A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis
BMC Psychiatry, 16, 126
DOI 10.1186/s12888-016-0827-4, PubMed 27146044
The role of childhood trauma in bipolar disorders
Int J Bipolar Disord, 4 (1), 2
DOI 10.1186/s40345-015-0042-0, PubMed 26763504
Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders
Psychol Med, 47 (5), 902-912
DOI 10.1017/S0033291716003081, PubMed 27894372
Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders
Psychol Med, 47 (4), 669-679
DOI 10.1017/S0033291716002762, PubMed 27834153
Publications 2015
Attentional load modulates large-scale functional brain connectivity beyond the core attention networks
Neuroimage, 109, 260-72
DOI 10.1016/j.neuroimage.2015.01.026, PubMed 25595500
Functional connectivity indicates differential roles for the intraparietal sulcus and the superior parietal lobule in multiple object tracking
Neuroimage, 123, 129-37
DOI 10.1016/j.neuroimage.2015.08.029, PubMed 26299796
Polygenic risk scores in bipolar disorder subgroups
J Affect Disord, 183, 310-4
DOI 10.1016/j.jad.2015.05.021, PubMed 26047958
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
PLoS One, 10 (4), e0123057
DOI 10.1371/journal.pone.0123057, PubMed 25853426
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
PLoS One, 10 (5), e0128048
DOI 10.1371/journal.pone.0128048, PubMed 25978331
Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
PLoS Genet, 11 (11), e1005544
DOI 10.1371/journal.pgen.1005544, PubMed 26540268
Genome-wide association study identifies common variants associated with pharmacokinetics of psychotropic drugs
J Psychopharmacol, 29 (8), 884-91
DOI 10.1177/0269881115584469, PubMed 25944848
The development of insight and its relationship with suicidality over one year follow-up in patients with first episode psychosis
Schizophr Res, 162 (1-3), 97-102
DOI 10.1016/j.schres.2015.01.004, PubMed 25620119
Influence of light exposure during early life on the age of onset of bipolar disorder
J Psychiatr Res, 64, 1-8
DOI 10.1016/j.jpsychires.2015.03.013, PubMed 25862378
Psychosis: clinical insight and beliefs in immigrants in their first episode
Early Interv Psychiatry, 12 (2), 185-192
DOI 10.1111/eip.12297, PubMed 26663787
Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness
Am J Med Genet B Neuropsychiatr Genet, 171B (2), 276-89
DOI 10.1002/ajmg.b.32402, PubMed 26663532
Effects of haloperidol and aripiprazole on the human mesolimbic motivational system: A pharmacological fMRI study
Eur Neuropsychopharmacol, 25 (12), 2252-61
DOI 10.1016/j.euroneuro.2015.09.016, PubMed 26476705
No difference in frontal cortical activity during an executive functioning task after acute doses of aripiprazole and haloperidol
Front Hum Neurosci, 9, 296
DOI 10.3389/fnhum.2015.00296, PubMed 26074803
Assessing brain structural associations with working-memory related brain patterns in schizophrenia and healthy controls using linked independent component analysis
Neuroimage Clin, 9, 253-63
DOI 10.1016/j.nicl.2015.08.010, PubMed 26509112
Cognitive Effort and Schizophrenia Modulate Large-Scale Functional Brain Connectivity
Schizophr Bull, 41 (6), 1360-9
DOI 10.1093/schbul/sbv013, PubMed 25731885
Large-scale genomics unveil polygenic architecture of human cortical surface area
Nat Commun, 6, 7549
DOI 10.1038/ncomms8549, PubMed 26189703
Ongoing episode of major depressive disorder is not associated with elevated plasma levels of kynurenine pathway markers
Psychoneuroendocrinology, 56, 12-22
DOI 10.1016/j.psyneuen.2015.02.011, PubMed 25770856
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
Circulation, 131 (23), 2061-2069
DOI 10.1161/CIRCULATIONAHA.115.015489, PubMed 25862742
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus
Mol Psychiatry, 20 (12), 1588-95
DOI 10.1038/mp.2015.6, PubMed 25687773
Theory of mind in schizophrenia: error types and associations with symptoms
Schizophr Res, 162 (1-3), 42-6
DOI 10.1016/j.schres.2015.01.024, PubMed 25623602
MicroRNAs enrichment in GWAS of complex human phenotypes
BMC Genomics, 16 (1), 304
DOI 10.1186/s12864-015-1513-5, PubMed 25884492
Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders
Front Hum Neurosci, 9, 9
DOI 10.3389/fnhum.2015.00009, PubMed 25667571
Lithium treatment and hippocampal subfields and amygdala volumes in bipolar disorder
Bipolar Disord, 17 (5), 496-506
DOI 10.1111/bdi.12295, PubMed 25809287
High levels of anomalous self-experience are associated with longer duration of untreated psychosis
Early Interv Psychiatry, 11 (2), 133-138
DOI 10.1111/eip.12220, PubMed 25589153
No progressive brain changes during a 1-year follow-up of patients with first-episode psychosis
Psychol Med, 46 (3), 589-98
DOI 10.1017/S003329171500210X, PubMed 26526001
Cannabis use is associated with 3years earlier onset of schizophrenia spectrum disorder in a naturalistic, multi-site sample (N=1119)
Schizophr Res, 170 (1), 217-21
DOI 10.1016/j.schres.2015.11.027, PubMed 26682958
Common genetic variants influence human subcortical brain structures
Nature, 520 (7546), 224-9
DOI 10.1038/nature14101, PubMed 25607358
Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders
Nord J Psychiatry, 70 (4), 276-9
DOI 10.3109/08039488.2015.1095944, PubMed 26559242
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633
Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls
Acta Psychiatr Scand, 133 (1), 53-62
DOI 10.1111/acps.12467, PubMed 26189721
Genome-wide autozygosity is associated with lower general cognitive ability
Mol Psychiatry, 21 (6), 837-43
DOI 10.1038/mp.2015.120, PubMed 26390830
A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia
Biol Psychiatry, 80 (4), 323-330
DOI 10.1016/j.biopsych.2015.09.021, PubMed 26682468
Stability of executive functions in first episode psychosis: One year follow up study
Psychiatry Res, 228 (3), 475-81
DOI 10.1016/j.psychres.2015.05.060, PubMed 26165960
Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups
PLoS One, 10 (8), e0137223
DOI 10.1371/journal.pone.0137223, PubMed 26322892
Cigarette smoking is associated with thinner cingulate and insular cortices in patients with severe mental illness
J Psychiatry Neurosci, 40 (4), 241-9
DOI 10.1503/jpn.140163, PubMed 25672482
The brain functional connectome is robustly altered by lack of sleep
Neuroimage, 127, 324-332
DOI 10.1016/j.neuroimage.2015.12.028, PubMed 26712339
Disintegration of Sensorimotor Brain Networks in Schizophrenia
Schizophr Bull, 41 (6), 1326-35
DOI 10.1093/schbul/sbv060, PubMed 25943122
Continued cannabis use at one year follow up is associated with elevated mood and lower global functioning in bipolar I disorder
BMC Psychiatry, 15, 11
DOI 10.1186/s12888-015-0389-x, PubMed 25651990
Cannabis use disorder is associated with greater illness severity in tobacco smoking patients with bipolar disorder
J Affect Disord, 190, 286-293
DOI 10.1016/j.jad.2015.10.023, PubMed 26544611
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ Res, 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Int J Epidemiol, 44 (5), 1706-21
DOI 10.1093/ije/dyv136, PubMed 26286434
Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons
PLoS One, 10 (11), e0143432
DOI 10.1371/journal.pone.0143432, PubMed 26587987
Brain structure abnormalities in first-episode psychosis patients with persistent apathy
Schizophr Res, 164 (1-3), 59-64
DOI 10.1016/j.schres.2015.03.001, PubMed 25818626
Vitamin D status in psychotic disorder patients and healthy controls--The influence of ethnic background
Psychiatry Res, 230 (2), 616-21
DOI 10.1016/j.psychres.2015.10.015, PubMed 26500071
Effects of ECT in treatment of depression: study protocol for a prospective neuroradiological study of acute and longitudinal effects on brain structure and function
BMC Psychiatry, 15, 94
DOI 10.1186/s12888-015-0477-y, PubMed 25927716
The promise and pitfalls of intranasally administering psychopharmacological agents for the treatment of psychiatric disorders
Mol Psychiatry, 21 (1), 29-38
DOI 10.1038/mp.2015.166, PubMed 26552590
Reduced heart rate variability in schizophrenia and bipolar disorder compared to healthy controls
Acta Psychiatr Scand, 133 (1), 44-52
DOI 10.1111/acps.12498, PubMed 26371411
Low-dose oxytocin delivered intranasally with Breath Powered device affects social-cognitive behavior: a randomized four-way crossover trial with nasal cavity dimension assessment
Transl Psychiatry, 5 (7), e602
DOI 10.1038/tp.2015.93, PubMed 26171983
Negative symptoms in schizophrenia show association with amygdala volumes and neural activation during affective processing
Acta Neuropsychiatr, 27 (4), 213-20
DOI 10.1017/neu.2015.11, PubMed 25777814
Negative symptoms in schizophrenia are associated with aberrant striato-cortical connectivity in a rewarded perceptual decision-making task
Neuroimage Clin, 8, 290-7
DOI 10.1016/j.nicl.2015.04.025, PubMed 26106553
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci
PLoS One, 10 (12), e0144531
DOI 10.1371/journal.pone.0144531, PubMed 26695485
Population genetic differentiation of height and body mass index across Europe
Nat Genet, 47 (11), 1357-62
DOI 10.1038/ng.3401, PubMed 26366552
Response to Kotzalidis et al
Am J Psychiatry, 172 (3), 294-5
DOI 10.1176/appi.ajp.2014.14101366r, PubMed 25727541
Response to Kellner and Fink
Am J Psychiatry, 172 (3), 295-6
DOI 10.1176/appi.ajp.2014.14101284r, PubMed 25727543
New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiology
Curr Opin Neurobiol, 36, 89-98
DOI 10.1016/j.conb.2015.10.008, PubMed 26555806
Association between serum lipids and membrane fatty acids and clinical characteristics in patients with schizophrenia
Acta Psychiatr Scand, 132 (4), 293-300
DOI 10.1111/acps.12388, PubMed 25597473
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Biol Psychiatry, 80 (4), 284-292
DOI 10.1016/j.biopsych.2015.10.009, PubMed 26681495
Serum level of venlafaxine is associated with better memory in psychotic disorders
Schizophr Res, 169 (1-3), 386-392
DOI 10.1016/j.schres.2015.10.021, PubMed 26516101
Delayed sleep phase: An important circadian subtype of sleep disturbance in bipolar disorders
J Affect Disord, 191, 156-63
DOI 10.1016/j.jad.2015.11.025, PubMed 26655861
Sleep problems in bipolar disorders: more than just insomnia
Acta Psychiatr Scand, 133 (5), 368-77
DOI 10.1111/acps.12523, PubMed 26590799
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
Nat Genet, 47 (5), 445-7
DOI 10.1038/ng.3246, PubMed 25807283
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
PLoS One, 10 (7), e0134202
DOI 10.1371/journal.pone.0134202, PubMed 26222050
ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide
Neuroimage, 145 (Pt B), 389-408
DOI 10.1016/j.neuroimage.2015.11.057, PubMed 26658930
An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies
PLoS Genet, 11 (12), e1005717
DOI 10.1371/journal.pgen.1005717, PubMed 26714184
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment
Am J Med Genet B Neuropsychiatr Genet, 168B (5), 363-73
DOI 10.1002/ajmg.b.32319, PubMed 25951819
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
Mol Psychiatry, 21 (4), 547-53
DOI 10.1038/mp.2015.63, PubMed 26033243
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
Mol Psychiatry, 21 (4), 585
DOI 10.1038/mp.2015.118, PubMed 26283641
Brain structure characteristics in intellectually superior schizophrenia
Psychiatry Res, 232 (1), 123-9
DOI 10.1016/j.pscychresns.2015.02.005, PubMed 25754688
To the editors: Reply to Anna R. Docherty
Psychiatry Res, 233 (3), 497
DOI 10.1016/j.pscychresns.2015.07.022, PubMed 26319295
A social path to functioning in schizophrenia: From social self-efficacy through negative symptoms to social functional capacity
Psychiatry Res, 228 (3), 803-7
DOI 10.1016/j.psychres.2015.05.019, PubMed 26089018
Genome-wide analysis of attention deficit hyperactivity disorder in Norway
PLoS One, 10 (4), e0122501
DOI 10.1371/journal.pone.0122501, PubMed 25875332
Unhelpful metacognitive beliefs in early psychosis are associated with affective symptoms and childhood social adjustment
Schizophr Res, 169 (1-3), 280-285
DOI 10.1016/j.schres.2015.10.026, PubMed 26519990
Publications 2014
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
Mol Psychiatry, 20 (2), 207-14
DOI 10.1038/mp.2013.195, PubMed 24468824
Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes
Hypertension, 63 (4), 819-26
DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
Shared common variants in prostate cancer and blood lipids
Int J Epidemiol, 43 (4), 1205-14
DOI 10.1093/ije/dyu090, PubMed 24786909
Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study
J Affect Disord, 167, 104-11
DOI 10.1016/j.jad.2014.05.032, PubMed 24953482
Influence of birth cohort on age of onset cluster analysis in bipolar I disorder
Eur Psychiatry, 30 (1), 99-105
DOI 10.1016/j.eurpsy.2014.10.005, PubMed 25498240
The impact of immigration and visible minority status on psychosis symptom profile
Soc Psychiatry Psychiatr Epidemiol, 49 (11), 1747-57
DOI 10.1007/s00127-014-0897-x, PubMed 24927946
Childhood trauma mediates the association between ethnic minority status and more severe hallucinations in psychotic disorder
Psychol Med, 45 (1), 133-42
DOI 10.1017/S0033291714001135, PubMed 25065296
A genome-wide association study of anorexia nervosa
Mol Psychiatry, 19 (10), 1085-94
DOI 10.1038/mp.2013.187, PubMed 24514567
Working memory networks and activation patterns in schizophrenia and bipolar disorder: comparison with healthy controls
Br J Psychiatry, 204, 290-8
DOI 10.1192/bjp.bp.113.129254, PubMed 24434074
Environmental factors during adolescence associated with later development of psychotic disorders - a nested case-control study
Psychiatry Res, 215 (3), 579-85
DOI 10.1016/j.psychres.2013.12.048, PubMed 24495574
The plasma levels of various cytokines are increased during ongoing depression and are reduced to normal levels after recovery
Psychoneuroendocrinology, 45, 77-86
DOI 10.1016/j.psyneuen.2014.03.019, PubMed 24845179
The role of clusterin in amyloid-β-associated neurodegeneration
JAMA Neurol, 71 (2), 180-7
DOI 10.1001/jamaneurol.2013.4560, PubMed 24378367
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
Schizophr Res, 161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965
Risk factors of cycle acceleration in acutely admitted patients with bipolar disorder
Acta Psychiatr Scand, 130 (5), 388-96
DOI 10.1111/acps.12308, PubMed 24962060
Exploring the agreement between questionnaire information and DSM-IV diagnoses of comorbid psychopathology in children with autism spectrum disorders
Autism, 19 (4), 433-42
DOI 10.1177/1362361314526003, PubMed 24637430
Comparison of variants of canonical correlation analysis and partial least squares for combined analysis of MRI and genetic data
Neuroimage, 107, 289-310
DOI 10.1016/j.neuroimage.2014.12.025, PubMed 25527238
An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes
Neuropsychobiology, 69 (1), 25-30
DOI 10.1159/000356965, PubMed 24458227
Anomalous self-experience and childhood trauma in first-episode schizophrenia
Compr Psychiatry, 56, 35-41
DOI 10.1016/j.comppsych.2014.10.005, PubMed 25458477
In vivo hippocampal subfield volumes in schizophrenia and bipolar disorder
Biol Psychiatry, 77 (6), 581-8
DOI 10.1016/j.biopsych.2014.06.020, PubMed 25127742
Glutamate as a mediating transmitter for auditory hallucinations in schizophrenia: a (1)H MRS study
Schizophr Res, 161 (2-3), 252-60
DOI 10.1016/j.schres.2014.11.015, PubMed 25542859
Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls
Schizophr Bull, 41 (3), 736-43
DOI 10.1093/schbul/sbu152, PubMed 25392519
The effect of electroconvulsive therapy on neurocognitive function in treatment-resistant bipolar disorder depression
J Clin Psychiatry, 75 (11), e1306-13
DOI 10.4088/JCP.13m08960, PubMed 25470096
Cannabis use in first-treatment bipolar I disorder: relations to clinical characteristics
Early Interv Psychiatry, 10 (1), 36-44
DOI 10.1111/eip.12138, PubMed 24739233
Increased amygdala and visual cortex activity and functional connectivity towards stimulus novelty is associated with state anxiety
PLoS One, 9 (4), e96146
DOI 10.1371/journal.pone.0096146, PubMed 24755617
The human amygdala encodes value and space during decision making
Neuroimage, 101, 712-9
DOI 10.1016/j.neuroimage.2014.07.055, PubMed 25094017
The left inferior frontal gyrus is involved in adjusting response bias during a perceptual decision-making task
Brain Behav, 4 (3), 398-407
DOI 10.1002/brb3.223, PubMed 24944869
Increased mortality in schizophrenia due to cardiovascular disease - a non-systematic review of epidemiology, possible causes, and interventions
Front Psychiatry, 5, 137
DOI 10.3389/fpsyt.2014.00137, PubMed 25309466
Treatment-resistant bipolar depression: a randomized controlled trial of electroconvulsive therapy versus algorithm-based pharmacological treatment
Am J Psychiatry, 172 (1), 41-51
DOI 10.1176/appi.ajp.2014.13111517, PubMed 25219389
Cognitive Behavior Therapy in First-Episode Psychosis With a Focus on Depression, Anxiety, and Self-Esteem
Cogn. Behav. Pract., 21 (1), 43-54
Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders
J Psychiatr Res, 52, 57-62
DOI 10.1016/j.jpsychires.2014.01.017, PubMed 24534618
Polygenic risk score and the psychosis continuum model
Acta Psychiatr Scand, 130 (4), 311-7
DOI 10.1111/acps.12307, PubMed 24961959
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Brain Imaging Behav, 8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358
Neurocognitive Decrements are Present in Intellectually Superior Schizophrenia
Front Psychiatry, 5, 45
DOI 10.3389/fpsyt.2014.00045, PubMed 24847284
ANK3 gene expression in bipolar disorder and schizophrenia
Br J Psychiatry, 205 (3), 244-5
DOI 10.1192/bjp.bp.114.145433, PubMed 24809399
Covariate-modulated local false discovery rate for genome-wide association studies
Bioinformatics, 30 (15), 2098-104
DOI 10.1093/bioinformatics/btu145, PubMed 24711653
Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders
World J Biol Psychiatry, 16 (3), 171-9
DOI 10.3109/15622975.2014.953011, PubMed 25264289
Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma
Psychiatry Res, 218 (1-2), 252-5
DOI 10.1016/j.psychres.2014.03.046, PubMed 24803185
Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders
J Psychiatr Res, 59, 14-21
DOI 10.1016/j.jpsychires.2014.08.011, PubMed 25246365
Psychometric properties of the Affective Lability Scale (54 and 18-item version) in patients with bipolar disorder, first-degree relatives, and healthy controls
J Affect Disord, 172, 375-80
DOI 10.1016/j.jad.2014.10.028, PubMed 25451440
Publications 2013
A comprehensive family-based replication study of schizophrenia genes
JAMA Psychiatry, 70 (6), 573-81
DOI 10.1001/jamapsychiatry.2013.288, PubMed 23894747
Neurocognitive features in subgroups of bipolar disorder
Bipolar Disord, 15 (3), 272-83
DOI 10.1111/bdi.12061, PubMed 23521608
Would Kraepelin reconsider the distinction between schizophrenia and bipolar disorder if he had access to recent molecular genetics evidence?
Acta Neuropsychiatr., 25 (6), 309-310
DOI 10.1017/neu.2013.62
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
Am J Hum Genet, 92 (2), 197-209
DOI 10.1016/j.ajhg.2013.01.001, PubMed 23375658
Boosting the power of schizophrenia genetics by leveraging new statistical tools
Schizophr Bull, 40 (1), 13-7
DOI 10.1093/schbul/sbt168, PubMed 24319118
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
PLoS Genet, 9 (4), e1003455
DOI 10.1371/journal.pgen.1003455, PubMed 23637625
ZNF804A and cortical thickness in schizophrenia and bipolar disorder
Psychiatry Res, 212 (2), 154-7
DOI 10.1016/j.pscychresns.2013.01.007, PubMed 23562677
Aversive event anticipation affects connectivity between the ventral striatum and the orbitofrontal cortex in an fMRI avoidance task
PLoS One, 8 (6), e68494
DOI 10.1371/journal.pone.0068494, PubMed 23826392
Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis
Acta Psychiatr Scand, 128 (3), 149-62
DOI 10.1111/acps.12133, PubMed 23617548
Self-reported symptoms and health service use in adolescence in persons who later develop psychotic disorders: a prospective case-control study
Early Interv Psychiatry, 9 (3), 221-7
DOI 10.1111/eip.12102, PubMed 24224904
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nat Genet, 45 (9), 984-94
DOI 10.1038/ng.2711, PubMed 23933821
Heart fatty acid binding protein and Aβ-associated Alzheimer's neurodegeneration
Mol Neurodegener, 8, 39
DOI 10.1186/1750-1326-8-39, PubMed 24088526
Evidence for reduced dentate gyrus and fimbria volume in bipolar II disorder
Bipolar Disord, 15 (2), 167-76
DOI 10.1111/bdi.12046, PubMed 23317454
Bipolar II disorder is associated with thinning of prefrontal and temporal cortices involved in affect regulation
Bipolar Disord, 15 (8), 855-64
DOI 10.1111/bdi.12117, PubMed 23980618
Childhood trauma is associated with severe clinical characteristics of bipolar disorders
J Clin Psychiatry, 74 (10), 991-8
DOI 10.4088/JCP.13m08353, PubMed 24229750
Apathy, poor verbal memory and male gender predict lower psychosocial functioning one year after the first treatment of psychosis
Psychiatry Res, 210 (1), 55-61
DOI 10.1016/j.psychres.2013.02.007, PubMed 23489592
A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder
PLoS One, 8 (12), e81052
DOI 10.1371/journal.pone.0081052, PubMed 24349030
Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia
J Affect Disord, 163, 110-4
DOI 10.1016/j.jad.2013.12.018, PubMed 24461634
Object relations, reality testing, and social withdrawal in schizophrenia and bipolar disorder
J Nerv Ment Dis, 201 (3), 222-5
DOI 10.1097/NMD.0b013e3182848ae0, PubMed 23407207
Anomalous self-experiences contribute independently to social dysfunction in the early phases of schizophrenia and psychotic bipolar disorder
Compr Psychiatry, 55 (3), 475-82
DOI 10.1016/j.comppsych.2013.11.010, PubMed 24378241
Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder
Psychol Med, 44 (5), 975-85
DOI 10.1017/S0033291713001529, PubMed 23803260
Normal birth weight variation is related to cortical morphology across the psychosis spectrum
Schizophr Bull, 40 (2), 410-9
DOI 10.1093/schbul/sbt005, PubMed 23419977
Social functioning in first contact mania: clinical and neurocognitive correlates
Compr Psychiatry, 54 (5), 432-8
DOI 10.1016/j.comppsych.2012.12.016, PubMed 23351832
European Network of Bipolar Research Expert Centre (ENBREC): a network to foster research and promote innovative care
Int J Bipolar Disord, 1, 2
DOI 10.1186/2194-7511-1-2, PubMed 25505669
Genetic clustering on the hippocampal surface for genome-wide association studies
Med Image Comput Comput Assist Interv, 16 (Pt 2), 690-7
DOI 10.1007/978-3-642-40763-5_85, PubMed 24579201
Genetic Clustering on the Hippocampal Surface for Genome-Wide Association Studies
LECT NOTES COMPUT SC, 8150, 690-697
Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder
Schizophr Res, 145 (1-3), 36-42
DOI 10.1016/j.schres.2012.12.023, PubMed 23403415
Neurocognitive profiles in treatment-resistant bipolar I and bipolar II disorder depression
BMC Psychiatry, 13, 105
DOI 10.1186/1471-244X-13-105, PubMed 23557429
Indications of a dose-response relationship between cannabis use and age at onset in bipolar disorder
Psychiatry Res, 215 (1), 101-4
DOI 10.1016/j.psychres.2013.10.029, PubMed 24262665
One year follow-up of alcohol and illicit substance use in first-episode psychosis: does gender matter?
Compr Psychiatry, 55 (2), 274-82
DOI 10.1016/j.comppsych.2013.08.018, PubMed 24262129
Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
BMC Psychiatry, 13, 97
DOI 10.1186/1471-244X-13-97, PubMed 23522391
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
Mol Psychiatry, 19 (2), 168-74
DOI 10.1038/mp.2013.166, PubMed 24342994
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Nat Genet, 45 (6), 670-5
DOI 10.1038/ng.2616, PubMed 23603763
Clinical characteristics in schizophrenia patients with or without suicide attempts and non-suicidal self-harm--a cross-sectional study
BMC Psychiatry, 13, 255
DOI 10.1186/1471-244X-13-255, PubMed 24106884
Migrant background and ethnic minority status as predictors for duration of untreated psychosis
Early Interv Psychiatry, 9 (1), 61-5
DOI 10.1111/eip.12106, PubMed 24225002
Reduced brain cortical folding in schizophrenia revealed in two independent samples
Schizophr Res, 152 (2-3), 333-8
DOI 10.1016/j.schres.2013.11.032, PubMed 24365403
Motivation alters response bias and neural activation patterns in a perceptual decision-making task
Neuroscience, 238, 135-47
DOI 10.1016/j.neuroscience.2013.02.015, PubMed 23428623
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
Mol Psychiatry, 19 (9), 1017-1024
DOI 10.1038/mp.2013.138, PubMed 24280982
Occupational outcome in bipolar disorder is not predicted by premorbid functioning and intelligence
Bipolar Disord, 15 (3), 294-305
DOI 10.1111/bdi.12056, PubMed 23527993
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs
PLoS Genet, 9 (4), e1003449
DOI 10.1371/journal.pgen.1003449, PubMed 23637621
No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes
J Affect Disord, 151 (1), 291-7
DOI 10.1016/j.jad.2013.06.008, PubMed 23820096
CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
PLoS One, 8 (2), e56970
DOI 10.1371/journal.pone.0056970, PubMed 23437284
Frontotemporal hypoactivity during a reality monitoring paradigm is associated with delusions in patients with schizophrenia spectrum disorders
Cogn Neuropsychiatry, 19 (2), 97-115
DOI 10.1080/13546805.2013.776495, PubMed 23756081
Social cognition and clinical insight in schizophrenia and bipolar disorder
J Nerv Ment Dis, 201 (6), 445-51
DOI 10.1097/NMD.0b013e31829480c8, PubMed 23686158
The neural correlates of cognitive control in bipolar I disorder: an fMRI study of medial frontal cortex activation during a Go/No-go task
Neurosci Lett, 549, 51-6
DOI 10.1016/j.neulet.2013.06.010, PubMed 23778236
Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders
Psychol Med, 44 (8), 1653-62
DOI 10.1017/S0033291713002316, PubMed 24028906
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
Prog Neuropsychopharmacol Biol Psychiatry, 46, 181-8
DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786
Publications 2012
An association between affective lability and executive functioning in bipolar disorder
Psychiatry Res, 198 (1), 58-61
DOI 10.1016/j.psychres.2011.12.044, PubMed 22405635
D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
Eur Arch Psychiatry Clin Neurosci, 262 (7), 549-56
DOI 10.1007/s00406-012-0313-z, PubMed 22454242
Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
Psychiatry Res, 197 (3), 327-36
DOI 10.1016/j.psychres.2011.12.036, PubMed 22417934
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans
Proc Natl Acad Sci U S A, 109 (10), 3985-90
DOI 10.1073/pnas.1105829109, PubMed 22343285
Impact of sunlight on the age of onset of bipolar disorder
Bipolar Disord, 14 (6), 654-63
DOI 10.1111/j.1399-5618.2012.01025.x, PubMed 22612720
Social dysfunction in first-episode psychosis and relations to neurocognition, duration of untreated psychosis and clinical symptoms
Psychiatry Res, 207 (1-2), 33-9
DOI 10.1016/j.psychres.2012.10.010, PubMed 23153893
Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach
Transl Psychiatry, 2 (7), e143
DOI 10.1038/tp.2012.67, PubMed 22828495
Linkage-disequilibrium-based binning affects the interpretation of GWASs
Am J Hum Genet, 90 (4), 727-33
DOI 10.1016/j.ajhg.2012.02.025, PubMed 22444669
Apolipoprotein E epsilon4 does not modulate amyloid-β-associated neurodegeneration in preclinical Alzheimer disease
AJNR Am J Neuroradiol, 34 (3), 505-10
DOI 10.3174/ajnr.A3267, PubMed 22976236
Up-regulation of NOTCH4 gene expression in bipolar disorder
Am J Psychiatry, 169 (12), 1292-300
DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060
Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
Schizophr Res, 140 (1-3), 169-74
DOI 10.1016/j.schres.2012.06.040, PubMed 22817875
Diagnosis of dementia--automatic quantification of brain structures
Tidsskr Nor Laegeforen, 132 (15), 1747-51
DOI 10.4045/tidsskr.12.0148, PubMed 22929941
Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders
PLoS One, 7 (2), e31687
DOI 10.1371/journal.pone.0031687, PubMed 22384057
Risk factors related to lifetime suicide attempts in acutely admitted bipolar disorder inpatients
Bipolar Disord, 14 (7), 727-34
DOI 10.1111/bdi.12004, PubMed 22998124
Object relations and reality testing in schizophrenia, bipolar disorders, and healthy controls: differences in profiles and clinical correlates
Compr Psychiatry, 53 (8), 1200-7
DOI 10.1016/j.comppsych.2012.04.003, PubMed 22578986
Selective aggregation of self-disorders in first-treatment DSM-IV schizophrenia spectrum disorders
J Nerv Ment Dis, 200 (7), 632-6
DOI 10.1097/NMD.0b013e31825bfd6f, PubMed 22759943
Neurocognitive functioning in patients recently diagnosed with bipolar disorder
Bipolar Disord, 14 (3), 227-38
DOI 10.1111/j.1399-5618.2012.01004.x, PubMed 22548896
Executive function in early- and adult onset schizophrenia
Schizophr Res, 142 (1-3), 177-82
DOI 10.1016/j.schres.2012.10.006, PubMed 23102692
Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
J Psychiatry Neurosci, 37 (1), 53-7
DOI 10.1503/jpn.100175, PubMed 21693093
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder
PLoS One, 7 (4), e35424
DOI 10.1371/journal.pone.0035424, PubMed 22539971
Predictors of medication adherence in patients with schizophrenia and bipolar disorder
Acta Psychiatr Scand, 127 (1), 23-33
DOI 10.1111/j.1600-0447.2012.01911.x, PubMed 22900964
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Nature, 488 (7409), 96-9
DOI 10.1038/nature11283, PubMed 22801501
Variant of TREM2 associated with the risk of Alzheimer's disease
N Engl J Med, 368 (2), 107-16
DOI 10.1056/NEJMoa1211103, PubMed 23150908
Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia
Psychiatr Genet, 22 (5), 263-4
DOI 10.1097/YPG.0b013e32834f3558, PubMed 22157635
Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
Am J Med Genet B Neuropsychiatr Genet, 159B (6), 722-30
DOI 10.1002/ajmg.b.32076, PubMed 22815203
Is there an optimal factor structure of the Positive and Negative Syndrome Scale in patients with first-episode psychosis?
Scand J Psychol, 54 (2), 160-5
DOI 10.1111/sjop.12017, PubMed 23252448
High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
Compr Psychiatry, 54 (2), 123-7
DOI 10.1016/j.comppsych.2012.06.009, PubMed 22901835
Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
Behav Brain Funct, 8, 24
DOI 10.1186/1744-9081-8-24, PubMed 22594806
Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
Neuroimage, 70, 143-9
DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
Self-harm in patients with schizophrenia spectrum disorders
Arch Suicide Res, 16 (2), 111-23
DOI 10.1080/13811118.2012.667328, PubMed 22551042
Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
Twin Res Hum Genet, 15 (3), 273-85
DOI 10.1017/thg.2012.5, PubMed 22856363
Effect of relevance on amygdala activation and association with the ventral striatum
Neuroimage, 62 (1), 95-101
DOI 10.1016/j.neuroimage.2012.04.035, PubMed 22546319
Schizophrenia patients with and without post-traumatic stress disorder (PTSD) have different mood symptom levels but same cognitive functioning
Acta Psychiatr Scand, 127 (6), 455-63
DOI 10.1111/acps.12041, PubMed 23176609
Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder
Biol Psychiatry, 71 (6), 552-60
DOI 10.1016/j.biopsych.2011.11.026, PubMed 22281121
Cannabis use and premorbid functioning as predictors of poorer neurocognition in schizophrenia spectrum disorder
Schizophr Res, 143 (1), 84-9
DOI 10.1016/j.schres.2012.10.021, PubMed 23178107
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population
Am J Med Genet B Neuropsychiatr Genet, 159B (8), 981-6
DOI 10.1002/ajmg.b.32104, PubMed 23076983
Identification of common variants associated with human hippocampal and intracranial volumes
Nat Genet, 44 (5), 552-61
DOI 10.1038/ng.2250, PubMed 22504417
Common variant at 16p11.2 conferring risk of psychosis
Mol Psychiatry, 19 (1), 108-14
DOI 10.1038/mp.2012.157, PubMed 23164818
Occupational functioning, symptoms and neurocognition in patients with psychotic disorders: investigating subgroups based on social security status
Soc Psychiatry Psychiatr Epidemiol, 48 (6), 863-74
DOI 10.1007/s00127-012-0598-2, PubMed 23064396
Factors associated with occupational and academic status in patients with first-episode psychosis with a particular focus on neurocognition
Soc Psychiatry Psychiatr Epidemiol, 47 (11), 1763-73
DOI 10.1007/s00127-012-0477-x, PubMed 22310699
Arousal Modulates Activity in the Medial Temporal Lobe during a Short-Term Relational Memory Task
Front Hum Neurosci, 5, 177
DOI 10.3389/fnhum.2011.00177, PubMed 22291626
Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
Biol Psychiatry, 72 (8), 645-50
DOI 10.1016/j.biopsych.2012.02.040, PubMed 22560537
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders
Transl Psychiatry, 2 (5), e112
DOI 10.1038/tp.2012.39, PubMed 22832956
Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
Psychiatry Res, 198 (3), 495-500
DOI 10.1016/j.psychres.2011.12.045, PubMed 22472845
Publications 2011
Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
Biol Psychiatry, 70 (7), 696-8
DOI 10.1016/j.biopsych.2011.02.034, PubMed 21514568
Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
Eur Neuropsychopharmacol, 21 (9), 700-4
DOI 10.1016/j.euroneuro.2010.12.008, PubMed 21295953
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia
Arch Gen Psychiatry, 68 (8), 781-90
DOI 10.1001/archgenpsychiatry.2011.81, PubMed 21810643
Perceived discrimination is associated with severity of positive and depression/anxiety symptoms in immigrants with psychosis: a cross-sectional study
BMC Psychiatry, 11, 77
DOI 10.1186/1471-244X-11-77, PubMed 21548949
Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
BMC Psychiatry, 11, 126
DOI 10.1186/1471-244X-11-126, PubMed 21812996
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
Psychiatr Genet, 21 (4), 214-5
DOI 10.1097/YPG.0b013e328341e020, PubMed 21712758
Evidence for impaired neocortical synaptic plasticity in bipolar II disorder
Biol Psychiatry, 71 (1), 68-74
DOI 10.1016/j.biopsych.2011.09.026, PubMed 22036034
The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
J Affect Disord, 135 (1-3), 43-50
DOI 10.1016/j.jad.2011.08.006, PubMed 21880373
Verbal learning contributes to cognitive insight in schizophrenia independently of affective and psychotic symptoms
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1059-63
DOI 10.1016/j.pnpbp.2011.02.021, PubMed 21392553
At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia
Biol Psychiatry, 70 (1), 59-63
DOI 10.1016/j.biopsych.2011.01.031, PubMed 21414605
Brain cortical thickness and surface area correlates of neurocognitive performance in patients with schizophrenia, bipolar disorder, and healthy adults
J Int Neuropsychol Soc, 17 (6), 1080-93
DOI 10.1017/S1355617711001081, PubMed 22013998
Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1122-30
DOI 10.1016/j.pnpbp.2011.03.014, PubMed 21457744
The association between anomalous self-experience and suicidality in first-episode schizophrenia seems mediated by depression
Compr Psychiatry, 53 (5), 456-60
DOI 10.1016/j.comppsych.2011.07.005, PubMed 21871617
The association between self-disorders and neurocognitive dysfunction in schizophrenia
Schizophr Res, 135 (1-3), 79-83
DOI 10.1016/j.schres.2011.11.015, PubMed 22137461
Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
J Psychiatr Res, 45 (12), 1608-16
DOI 10.1016/j.jpsychires.2011.08.003, PubMed 21889167
The genetic structure of the Swedish population
PLoS One, 6 (8), e22547
DOI 10.1371/journal.pone.0022547, PubMed 21829632
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia
Biol Psychiatry, 70 (1), 35-42
DOI 10.1016/j.biopsych.2011.01.030, PubMed 21439553
Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness
Am J Psychiatry, 168 (4), 408-17
DOI 10.1176/appi.ajp.2010.09111660, PubMed 21324950
Cognitive and clinical factors are associated with service engagement in early-phase schizophrenia spectrum disorders
J Nerv Ment Dis, 199 (3), 176-82
DOI 10.1097/NMD.0b013e31820bc2f9, PubMed 21346488
Combinations of SNPs related to signal transduction in bipolar disorder
PLoS One, 6 (8), e23812
DOI 10.1371/journal.pone.0023812, PubMed 21897858
Excessive cannabis use is associated with earlier age at onset in bipolar disorder
Eur Arch Psychiatry Clin Neurosci, 261 (6), 397-405
DOI 10.1007/s00406-011-0188-4, PubMed 21267743
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
J Psychiatr Res, 46 (2), 271-8
DOI 10.1016/j.jpsychires.2011.11.001, PubMed 22126837
Copy number variations in affective disorders and meta-analysis
Psychiatr Genet, 21 (6), 319-22
DOI 10.1097/YPG.0b013e3283463deb, PubMed 21451435
Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes
Genet Epidemiol, 35 (5), 318-32
DOI 10.1002/gepi.20580, PubMed 21484861
Severe social anxiety in early psychosis is associated with poor premorbid functioning, depression, and reduced quality of life
Compr Psychiatry, 53 (5), 434-40
DOI 10.1016/j.comppsych.2011.06.002, PubMed 21821242
Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis
BMC Psychiatry, 11, 136
DOI 10.1186/1471-244X-11-136, PubMed 21854599
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples
Am J Med Genet B Neuropsychiatr Genet, 156 (2), 215-24
DOI 10.1002/ajmg.b.31160, PubMed 21302350
Despite clinical differences, bipolar disorder patients from acute wards and outpatient clinics have similar educational and disability levels compared to the general population
J Affect Disord, 132 (1-2), 209-15
DOI 10.1016/j.jad.2011.02.025, PubMed 21440307
Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1100-7
DOI 10.1016/j.pnpbp.2011.03.008, PubMed 21420462
Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
J Clin Psychiatry, 72 (11), 1515-21
DOI 10.4088/JCP.10m06068yel, PubMed 21367348
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
Hum Mol Genet, 20 (20), 4076-81
DOI 10.1093/hmg/ddr325, PubMed 21791550
Identification of low-frequency variants associated with gout and serum uric acid levels
Nat Genet, 43 (11), 1127-30
DOI 10.1038/ng.972, PubMed 21983786
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
Am J Med Genet B Neuropsychiatr Genet, 156B (8), 969-74
DOI 10.1002/ajmg.b.31244, PubMed 21972176
Prefrontal hyperactivation during a working memory task in early-onset schizophrenia spectrum disorders: an fMRI study
Psychiatry Res, 194 (3), 257-262
DOI 10.1016/j.pscychresns.2011.05.011, PubMed 22079661
Dual association of a TRKA polymorphism with schizophrenia
Psychiatr Genet, 21 (3), 125-31
DOI 10.1097/YPG.0b013e3283437194, PubMed 21317683
Sex differences in neuropsychological performance and social functioning in schizophrenia and bipolar disorder
Neuropsychology, 25 (4), 499-510
DOI 10.1037/a0022677, PubMed 21463042
Acta Neuropsychiatrica and Scandinavian College of Neuropsychopharmacology (SCNP)
Acta Neuropsychiatr, 23 (5), 199-200
DOI 10.1111/j.1601-5215.2011.00602.x, PubMed 28183387
Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
Schizophr Bull, 38 (1), 15-22
DOI 10.1093/schbul/sbr113, PubMed 21908796
Publications 2010
Decreased self-reported arousal in schizophrenia during aversive picture viewing compared to bipolar disorder and healthy controls
Psychiatry Res, 185 (3), 309-14
DOI 10.1016/j.psychres.2010.07.026, PubMed 20724003
Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
Psychiatry Res, 180 (2-3), 63-7
DOI 10.1016/j.psychres.2009.11.018, PubMed 20580984
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
J Psychiatr Res, 44 (12), 748-53
DOI 10.1016/j.jpsychires.2010.02.002, PubMed 20185149
Intron 12 in NTRK3 is associated with bipolar disorder
Psychiatry Res, 185 (3), 358-62
DOI 10.1016/j.psychres.2010.05.011, PubMed 20554328
Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
Schizophr Res, 123 (2-3), 257-62
DOI 10.1016/j.schres.2010.07.018, PubMed 20685083
Suicidality before and in the early phases of first episode psychosis
Schizophr Res, 119 (1-3), 11-7
DOI 10.1016/j.schres.2010.03.022, PubMed 20399077
Neurocognitive functioning and suicidality in schizophrenia spectrum disorders
Compr Psychiatry, 52 (2), 156-63
DOI 10.1016/j.comppsych.2010.06.001, PubMed 21295222
A cross-sectional study of vitamin D deficiency among immigrants and Norwegians with psychosis compared to the general population
J Clin Psychiatry, 71 (12), 1598-604
DOI 10.4088/JCP.09m05299yel, PubMed 20441728
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
Mol Psychiatry, 16 (11), 1117-29
DOI 10.1038/mp.2010.96, PubMed 20838396
A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
J Affect Disord, 126 (1-2), 312-6
DOI 10.1016/j.jad.2010.04.007, PubMed 20451256
Apathy in first episode psychosis patients: one year follow up
Schizophr Res, 116 (1), 20-6
DOI 10.1016/j.schres.2009.10.014, PubMed 19948392
Investigating relationships between cortical thickness and cognitive performance in patients with schizophrenia and healthy adults
Psychiatry Res, 182 (2), 123-33
DOI 10.1016/j.pscychresns.2010.01.001, PubMed 20456929
An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
Prog Neuropsychopharmacol Biol Psychiatry, 34 (7), 1259-65
DOI 10.1016/j.pnpbp.2010.07.001, PubMed 20638435
Validation of the Norwegian version of the Social Functioning Scale (SFS) for schizophrenia and bipolar disorder
Scand J Psychol, 51 (6), 525-33
DOI 10.1111/j.1467-9450.2010.00839.x, PubMed 20642739
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study
Schizophr Res, 127 (1-3), 270-2
DOI 10.1016/j.schres.2010.10.002, PubMed 21030213
Osteoprotegerin levels in patients with severe mental disorders
J Psychiatry Neurosci, 35 (5), 304-10
DOI 10.1503/jpn.090088, PubMed 20569643
The validity of d prime as a working memory index: results from the "Bergen n-back task"
J Clin Exp Neuropsychol, 32 (8), 871-80
DOI 10.1080/13803391003596421, PubMed 20383801
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia
Hum Mol Genet, 19 (7), 1379-86
DOI 10.1093/hmg/ddq009, PubMed 20071346
Medication adherence in outpatients with severe mental disorders: relation between self-reports and serum level
J Clin Psychopharmacol, 30 (2), 169-75
DOI 10.1097/JCP.0b013e3181d2191e, PubMed 20520290
The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder
BMC Psychiatry, 10, 16
DOI 10.1186/1471-244X-10-16, PubMed 20178636
Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
Biol Psychiatry, 69 (1), 90-6
DOI 10.1016/j.biopsych.2010.07.035, PubMed 20950796
Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
Am J Med Genet B Neuropsychiatr Genet, 153B (1), 86-96
DOI 10.1002/ajmg.b.30958, PubMed 19350560
Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study
BMC Psychiatry, 10, 9
DOI 10.1186/1471-244X-10-9, PubMed 20105311
Treatment delay and excessive substance use in bipolar disorder
J Nerv Ment Dis, 198 (9), 628-33
DOI 10.1097/NMD.0b013e3181ef3ef4, PubMed 20823723
Impact of cognitive performance on the reproducibility of fMRI activation in schizophrenia
J Psychiatry Neurosci, 35 (6), 378-89
DOI 10.1503/jpn.090103, PubMed 20731962
The use of screening instruments for detecting alcohol and other drug use disorders in first-episode psychosis
Psychiatry Res, 177 (1-2), 228-34
DOI 10.1016/j.psychres.2010.01.007, PubMed 20178887
Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder
Biol Psychiatry, 68 (1), 41-50
DOI 10.1016/j.biopsych.2010.03.036, PubMed 20609836
Depression and depressive symptoms in first episode psychosis
J Nerv Ment Dis, 198 (1), 67-71
DOI 10.1097/NMD.0b013e3181c81fc0, PubMed 20061872
Assessment of social anxiety in first episode psychosis using the Liebowitz Social Anxiety scale as a self-report measure
Eur Psychiatry, 26 (2), 115-21
DOI 10.1016/j.eurpsy.2010.08.014, PubMed 21036553
The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 387-396
DOI 10.1002/ajmg.b.30991, PubMed 19526457
Bipolar disorder patients have similar levels of education but lower socio-economic status than the general population
J Affect Disord, 129 (1-3), 68-74
DOI 10.1016/j.jad.2010.08.012, PubMed 20832866
Psychosocial function in schizophrenia and bipolar disorder: Relationship to neurocognition and clinical symptoms
J Int Neuropsychol Soc, 16 (5), 771-83
DOI 10.1017/S1355617710000573, PubMed 20509984
SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 34 (8), 1500-6
DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085
Expanding the range of ZNF804A variants conferring risk of psychosis
Mol Psychiatry, 16 (1), 59-66
DOI 10.1038/mp.2009.149, PubMed 20048749
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
Am J Med Genet B Neuropsychiatr Genet, 153B (7), 1276-82
DOI 10.1002/ajmg.b.31098, PubMed 20872766
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 610-618
DOI 10.1002/ajmg.b.31030, PubMed 19746410
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
Schizophr Res, 122 (1-3), 31-7
DOI 10.1016/j.schres.2010.05.007, PubMed 20605701
Publications 2009
Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Psychiatr Genet, 19 (5), 273-4
DOI 10.1097/YPG.0b013e32832a4fcd, PubMed 19491717
Hormonal markers of metabolic dysregulation in patients with severe mental disorders after olanzapine treatment under real-life conditions
J Clin Psychopharmacol, 29 (2), 109-16
DOI 10.1097/JCP.0b013e31819b95fc, PubMed 19512971
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
Psychiatry Res, 168 (3), 256-8
DOI 10.1016/j.psychres.2008.08.007, PubMed 19223264
Delusions are associated with poor cognitive insight in schizophrenia
Schizophr Bull, 36 (4), 830-5
DOI 10.1093/schbul/sbn193, PubMed 19176474
Apathy is associated with executive functioning in first episode psychosis
BMC Psychiatry, 9, 1
DOI 10.1186/1471-244X-9-1, PubMed 19133132
Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
Bipolar Disord, 11 (7), 726-34
DOI 10.1111/j.1399-5618.2009.00757.x, PubMed 19839997
Copy number variations of chromosome 16p13.1 region associated with schizophrenia
Mol Psychiatry, 16 (1), 17-25
DOI 10.1038/mp.2009.101, PubMed 19786961
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations
Proc Natl Acad Sci U S A, 106 (36), 15483-8
DOI 10.1073/pnas.0901866106, PubMed 19717458
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
Neuropsychobiology, 59 (3), 142-50
DOI 10.1159/000218076, PubMed 19439994
Age at onset of bipolar disorder in a Norwegian catchment area sample
J Affect Disord, 124 (1-2), 174-7
DOI 10.1016/j.jad.2009.10.031, PubMed 19931918
Age at onset of first episode and time to treatment in in-patients with bipolar disorder
Br J Psychiatry, 194 (6), 559-60
DOI 10.1192/bjp.bp.108.054452, PubMed 19478300
Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
Neurobiol Dis, 34 (3), 518-24
DOI 10.1016/j.nbd.2009.03.011, PubMed 19344762
The impact of divergence time on the nature of population structure: an example from Iceland
PLoS Genet, 5 (6), e1000505
DOI 10.1371/journal.pgen.1000505, PubMed 19503599
Sex-dependent association of common variants of microcephaly genes with brain structure
Proc Natl Acad Sci U S A, 107 (1), 384-8
DOI 10.1073/pnas.0908454107, PubMed 20080800
Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia
Psychol Med, 40 (8), 1337-47
DOI 10.1017/S0033291709991620, PubMed 19891810
Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group
Schizophr Bull, 37 (1), 73-83
DOI 10.1093/schbul/sbp034, PubMed 19443616
Common variants conferring risk of schizophrenia
Nature, 460 (7256), 744-7
DOI 10.1038/nature08186, PubMed 19571808
No association between DGKH and bipolar disorder in a Scandinavian case-control sample
Psychiatr Genet, 19 (5), 269-72
DOI 10.1097/YPG.0b013e32832d302f, PubMed 19478689
Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
J Psychiatr Res, 43 (15), 1195-9
DOI 10.1016/j.jpsychires.2009.04.006, PubMed 19435634
Using the Wisconsin Card Sorting Test to assess learning potential in normal IQ schizophrenia: does it have potential?
Nord J Psychiatry, 63 (5), 405-11
DOI 10.1080/08039480902879941, PubMed 19365785
Social problem-solving in high-functioning schizophrenia: specific deficits in sending skills
Psychiatry Res, 165 (3), 215-23
DOI 10.1016/j.psychres.2007.11.009, PubMed 19136154
No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study
Bipolar Disord, 11 (3), 270-9
DOI 10.1111/j.1399-5618.2009.00680.x, PubMed 19419384
Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
Neuropsychobiology, 60 (1), 31-6
DOI 10.1159/000235799, PubMed 19729970
Publications 2008
Dyslipidemia independent of body mass in antipsychotic-treated patients under real-life conditions
J Clin Psychopharmacol, 28 (2), 132-7
DOI 10.1097/JCP.0b013e318166c4f7, PubMed 18344722
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
Schizophr Res, 107 (2-3), 242-8
DOI 10.1016/j.schres.2008.10.010, PubMed 19022628
Measurement of insight in patients with bipolar disorder: are self-rated scales developed for patients with schizophrenia applicable?
J Nerv Ment Dis, 196 (4), 333-5
DOI 10.1097/NMD.0b013e31816a62b2, PubMed 18414129
Beliefs about medications: measurement and relationship to adherence in patients with severe mental disorders
Acta Psychiatr Scand, 119 (1), 78-84
DOI 10.1111/j.1600-0447.2008.01279.x, PubMed 18983630
Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
Am J Med Genet B Neuropsychiatr Genet, 147B (6), 976-82
DOI 10.1002/ajmg.b.30671, PubMed 18165967
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Am J Med Genet B Neuropsychiatr Genet, 147B (7), 1089-100
DOI 10.1002/ajmg.b.30726, PubMed 18384059
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
Mol Psychiatry, 15 (5), 463-72
DOI 10.1038/mp.2008.110, PubMed 18936756
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
BMC Med Genet, 9, 39
DOI 10.1186/1471-2350-9-39, PubMed 18460190
The human amygdala is involved in general behavioral relevance detection: evidence from an event-related functional magnetic resonance imaging Go-NoGo task
Neuroscience, 156 (3), 450-5
DOI 10.1016/j.neuroscience.2008.07.066, PubMed 18775476
The level of illicit drug use is related to symptoms and premorbid functioning in severe mental illness
Acta Psychiatr Scand, 118 (4), 297-304
DOI 10.1111/j.1600-0447.2008.01244.x, PubMed 18759810
Disruption of the neurexin 1 gene is associated with schizophrenia
Hum Mol Genet, 18 (5), 988-96
DOI 10.1093/hmg/ddn351, PubMed 18945720
Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
Schizophr Res, 106 (2-3), 237-41
DOI 10.1016/j.schres.2008.08.024, PubMed 18818052
Neurocognitive profiles in bipolar I and bipolar II disorder: differences in pattern and magnitude of dysfunction
Bipolar Disord, 10 (2), 245-55
DOI 10.1111/j.1399-5618.2007.00492.x, PubMed 18271903
Large recurrent microdeletions associated with schizophrenia
Nature, 455 (7210), 232-6
DOI 10.1038/nature07229, PubMed 18668039
Emotion perception and learning potential: mediators between neurocognition and social problem-solving in schizophrenia?
J Int Neuropsychol Soc, 14 (2), 279-88
DOI 10.1017/S1355617708080314, PubMed 18282325
Can learning potential in schizophrenia be assessed with the standard CVLT-II? An exploratory study
Scand J Psychol, 49 (2), 179-86
DOI 10.1111/j.1467-9450.2008.00627.x, PubMed 18352988
Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients
Int J Neuropsychopharmacol, 11 (5), 679-84
DOI 10.1017/S1461145708008468, PubMed 18241359
Publications 2007
The level of cardiovascular risk factors in bipolar disorder equals that of schizophrenia: a comparative study
J Clin Psychiatry, 68 (6), 917-23
DOI 10.4088/jcp.v68n0614, PubMed 17592917
Measuring cognitive insight in schizophrenia and bipolar disorder: a comparative study
BMC Psychiatry, 7, 71
DOI 10.1186/1471-244X-7-71, PubMed 18072961
Psykiatriske forskningsmetoder
In Epidemiologiske og kliniske forskningsmetoder, Gyldendal akademisk, Oslo, [373]-[400]
BIBSYS 071650067
Brain expressed microRNAs implicated in schizophrenia etiology
PLoS One, 2 (9), e873
DOI 10.1371/journal.pone.0000873, PubMed 17849003
Differences in prevalence and patterns of substance use in schizophrenia and bipolar disorder
Psychol Med, 38 (9), 1241-9
DOI 10.1017/S003329170700236X, PubMed 18070373
Illicit drug use in patients with psychotic disorders compared with that in the general population: a cross-sectional study
Acta Psychiatr Scand, 117 (2), 133-8
DOI 10.1111/j.1600-0447.2007.01135.x, PubMed 18081921
The effect of gender on emotion perception in schizophrenia and bipolar disorder
Acta Psychiatr Scand, 116 (4), 263-70
DOI 10.1111/j.1600-0447.2007.00991.x, PubMed 17803756
Publications 2006
[Pharmacogenetics and tailored drug treatment in schizophrenia]
Tidsskr Nor Laegeforen, 126 (18), 2400-2
PubMed 16998555
Sociodemographic characteristics and cardiovascular risk factors in patients with severe mental disorders compared with the general population
J Clin Psychiatry, 67 (3), 425-33
DOI 10.4088/jcp.v67n0314, PubMed 16649830
Publications 2005
Should catatonia be part of the differential diagnosis of coma?
Nord J Psychiatry, 59 (6), 528-30
DOI 10.1080/08039480500360765, PubMed 16316908
Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease
J Neurochem, 95 (2), 553-62
DOI 10.1111/j.1471-4159.2005.03411.x, PubMed 16135087
Publications 2004
[Metabolic and cardiovascular adverse effects of modern antipsychotic agents]
Tidsskr Nor Laegeforen, 124 (2), 181-2
PubMed 14743232
Publications 2003
Oral dyskinesias and histopathological alterations in substantia nigra after long-term haloperidol treatment of old rats
Neuroscience, 122 (3), 717-25
DOI 10.1016/j.neuroscience.2003.08.058, PubMed 14622915
Memantine attenuates the increase in striatal preproenkephalin mRNA expression and development of haloperidol-induced persistent oral dyskinesias in rats
Brain Res, 994 (2), 188-92
DOI 10.1016/j.brainres.2003.09.035, PubMed 14642644
Publications 2002
Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression
Neurobiol Dis, 11 (3), 410-24
DOI 10.1006/nbdi.2002.0562, PubMed 12586550
[Schizophrenia and molecular genetics]
Tidsskr Nor Laegeforen, 122 (21), 2118-22
PubMed 12555650
Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid
Exp Neurol, 176 (1), 262-5
DOI 10.1006/exnr.2002.7933, PubMed 12093104
Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease
J Neurosci, 22 (5), 1592-9
DOI 10.1523/JNEUROSCI.22-05-01592.2002, PubMed 11880489
Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice
Free Radic Biol Med, 32 (9), 920-6
DOI 10.1016/s0891-5849(02)00784-0, PubMed 11978494
Publications 2001
Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease
Neurobiol Dis, 8 (3), 479-91
DOI 10.1006/nbdi.2001.0406, PubMed 11447996
Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice
Exp Neurol, 168 (2), 419-24
DOI 10.1006/exnr.2001.7633, PubMed 11259130
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP
Exp Neurol, 167 (1), 189-95
DOI 10.1006/exnr.2000.7525, PubMed 11161607
Lipoic acid improves survival in transgenic mouse models of Huntington's disease
Neuroreport, 12 (15), 3371-3
DOI 10.1097/00001756-200110290-00044, PubMed 11711888
Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease
Ann Neurol, 50 (1), 112-7
DOI 10.1002/ana.1085, PubMed 11456300
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid
Exp Neurol, 168 (2), 356-63
DOI 10.1006/exnr.2001.7627, PubMed 11259123
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation
J Neurochem, 77 (2), 383-90
DOI 10.1046/j.1471-4159.2001.00188.x, PubMed 11299300
Oral dyskinesias and morphological changes in rat striatum during long-term haloperidol administration
Psychopharmacology (Berl), 157 (1), 11-9
DOI 10.1007/s002130100767, PubMed 11512038
Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease
J Neurochem, 79 (6), 1246-9
DOI 10.1046/j.1471-4159.2001.00689.x, PubMed 11752065
Publications 2000
N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis
Neuroreport, 11 (11), 2491-3
DOI 10.1097/00001756-200008030-00029, PubMed 10943709
Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant
J Neurochem, 75 (2), 847-52
DOI 10.1046/j.1471-4159.2000.0750847.x, PubMed 10899963
Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis
Ann Neurol, 47 (4), 447-55
PubMed 10762155
Reduced number of striatal neurons expressing preprosomatostatin mRNA in rats with oral dyskinesias after long-term haloperidol administration
Neurosci Lett, 279 (1), 21-4
DOI 10.1016/s0304-3940(99)00939-8, PubMed 10670778
Neurotoxicity associated with neuroleptic-induced oral dyskinesias in rats. Implications for tardive dyskinesia?
Prog Neurobiol, 61 (5), 525-41
DOI 10.1016/s0301-0082(99)00064-7, PubMed 10748322
Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease
J Neurosci, 20 (12), 4389-97
DOI 10.1523/JNEUROSCI.20-12-04389.2000, PubMed 10844007
Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice
J Neurochem, 74 (5), 2108-19
DOI 10.1046/j.1471-4159.2000.0742108.x, PubMed 10800956
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
J Neurosci, 20 (1), 1-7
DOI 10.1523/JNEUROSCI.20-01-00001.2000, PubMed 10627575
Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity
Neuroreport, 11 (6), 1265-8
DOI 10.1097/00001756-200004270-00024, PubMed 10817604
No changes in dopamine D(1) receptor mRNA expressing neurons in the dorsal striatum of rats with oral movements induced by long-term haloperidol administration
Brain Res, 859 (2), 394-7
DOI 10.1016/s0006-8993(00)02017-5, PubMed 10719094
Publications 1999
The relationship between oral dyskinesias produced by long-term haloperidol treatment, the density of striatal preproenkephalin messenger RNA and enkephalin peptide, and the number of striatal neurons expressing preproenkephalin messenger RNA in rats
Neuroscience, 88 (1), 27-35
DOI 10.1016/s0306-4522(98)00175-4, PubMed 10051187
Coenzyme Q10 does not prevent oral dyskinesias induced by long-term haloperidol treatment of rats
Pharmacol Biochem Behav, 64 (3), 637-42
DOI 10.1016/s0091-3057(99)00118-5, PubMed 10548281
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
Nat Med, 5 (3), 347-50
DOI 10.1038/6568, PubMed 10086395
Publications 1998
Oral Dyskinesias and striatal lesions in rats after long-term co-treatment with haloperidol and 3-nitropropionic acid
Neuroscience, 87 (3), 639-48
DOI 10.1016/s0306-4522(98)00160-2, PubMed 9758230
Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity
J Neurochem, 71 (6), 2634-7
DOI 10.1046/j.1471-4159.1998.71062634.x, PubMed 9832165
Publications 1997
Non-functional CYP2D6 alleles and risk for neuroleptic-induced movement disorders in schizophrenic patients
Psychopharmacology (Berl), 131 (2), 174-9
DOI 10.1007/s002130050281, PubMed 9201806
Publications 1996
Inhibition by memantine of the development of persistent oral dyskinesias induced by long-term haloperidol treatment of rats
Br J Pharmacol, 119 (4), 751-7
DOI 10.1111/j.1476-5381.1996.tb15736.x, PubMed 8904651
Characterization and PCR-based detection of two different hybrid CYP2D7P/CYP2D6 alleles associated with the poor metabolizer phenotype
Pharmacogenetics, 6 (4), 319-28
DOI 10.1097/00008571-199608000-00005, PubMed 8873218
Correlation of vacuous chewing movements with morphological changes in rats following 1-year treatment with haloperidol
Psychopharmacology (Berl), 125 (3), 238-47
DOI 10.1007/BF02247334, PubMed 8815959
Estimation of the number of somatostatin neurons in the striatum: an in situ hybridization study using the optical fractionator method
J Comp Neurol, 370 (1), 11-22
DOI 10.1002/(SICI)1096-9861(19960617)370:1<11::AID-CNE2>3.0.CO;2-O, PubMed 8797153
Publications 1995
The rat model of tardive dyskinesia: relationship between vacuous chewing movements and gross motor activity during acute and long-term haloperidol treatment
Life Sci, 57 (24), 2263-72
DOI 10.1016/0024-3205(95)02219-9, PubMed 7475980
The mitochondrial toxin 3-nitropropionic acid induces vacuous chewing movements in rats. Implications for tardive dyskinesia?
Psychopharmacology (Berl), 119 (4), 474-6
DOI 10.1007/BF02245864, PubMed 7480528
Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
Pharmacogenetics, 5 (4), 215-23
DOI 10.1097/00008571-199508000-00005, PubMed 8528268
Publications 1994
GM1 ganglioside attenuates the development of vacuous chewing movements induced by long-term haloperidol treatment of rats
Psychopharmacology (Berl), 116 (4), 517-22
DOI 10.1007/BF02247487, PubMed 7701057
Tardive dyskinesia: behavioral effects of repeated intracerebroventricular haloperidol injections in rats do not confirm the kindling hypothesis
Pharmacol Biochem Behav, 49 (2), 309-12
DOI 10.1016/0091-3057(94)90426-x, PubMed 7824543
The relationship between motor effects in rats following acute and chronic haloperidol treatment
Psychopharmacology (Berl), 116 (1), 89-92
DOI 10.1007/BF02244876, PubMed 7862936